Multiple Sclerosis

Question 1

Immune-mediated progressive demyelinating (myelin sheath of neurons is damaged) disease of the CNS

Answer 1

Multiple Sclerosis

Question 2

A chronic degenerative progressive disease of the CNS. Characterized by small patches of demyelination in the brain & spinal cord.

Answer 2

Multiple Sclerosis

Question 2

To visualize small plaques, evaluate cause and effects of tx

Answer 2

MRI

Question 3

Diagnostic methods

Answer 3

1. MRI
2. Electrophoresis
3. Fluid-Attenuated-Inversion-Recovery (FLAIR)
4. Magnetic Resonance Spectroscopy

Question 4

Used to study CSF, abnormal IgG appears in the CSF

Answer 4

Eleectrophoresis

Question 5

A technique widely used to separate and identify serum proteins and other substances up to 95% of pt

Answer 5

Electrophoresis

Question 6

Able to detect two or three times the number of lesions seen in MRI, employ a long inversion time to nullify signals from fluids

Answer 6

Fluid-Attenuated-Inversion-Recovery (FLAIR)

Question 7

Decreased levels of N-Acetyl Aspartate (NAA) suggest presence of axonal damage

Answer 7

Magnetic Resonance Spectroscopy

Question 8

The second most concentrated molecule in the brain after the amino acid glutamate

Answer 8

N-Acetylaspartate