Multiple Myeloma

Question 1

Features characterising MM

Answer 1

‘CRAB’ features

• Calcium (elevated)
• Renal failure (raised creatinine)
• Anaemia/Antibodies
• Bone lesions

Question 2

> 10% plasma cells in bone marrow aspirate

Answer 2

Evidence of MM bone lesion

Question 3

Serum monoclonal protein >30g/L

Answer 3

Evidence of MM characteristic monoclonal antibodies

Question 4

Broad marker raised in bile duct disease and certain bone conditions (esp Paget’s)

Answer 4

ALP