MULTIMODAL IMAGING Flashcards
What area of brain is associated with attention related issues?
ANTERIOR CINGULATE
What is Axial Diffusivity?
refers to the magnitude of diffusion PARALLEL TO FIBR TRACTS
What is Radial Diffusivity?
The apparent water diffusion in the direction PERPENDICULAR TO THE AXON FIBERS
Pronounce Neurite
Neur write
What is meant by ISOTROPY?
ISOTROPHY occurs when the diffusion of water is entirely uninhibited and movement is uniform in all directions
NODDI enables the estimation of three key aspects of neural tissue at each voxel:
Neurite Density Index (NDI), which quantifies the packing density of axons or dendrites;
Orientation Dispersion Index (ODI),which assesses the orientation coherence of neurites,
Free Water Fraction (FWF), which estimates the extent of CSF contamination
Pronounce ISOTROPY
ICE OTT ROW FEE
Pronounce ANISOTROPHY
AN ICE OTT ROW FEE
What is ANISOTROPY?
There is a directionality in the movement of water
FRACTIONAL ANISOTROPY
The degree of anisotropy of water molecules.
0 is uninhibited movement of water
1 is fully anisotropic or restricted.
NODDI
Neurite Orientation Dispersion and Density Imaging
What is a Neurite?
Axons and dendrites
Projections of neurons
NDI
Neurite Density Index
Represents axonal Density in white matter
ODI
Orientation Dispersion index
of Neurites
Higher in loosely organized white matter
Lower in tracts that are largely parallel fiber bundles such as corpus callosum
FISO
volume Fraction of Isotropic diffusion compartment
Estimates free water content.
What is a dendrite?
Dendrites transmitt impulses to cell body
Are shorter
Heavily branched
What is an axon?
Carry nerve impulses away from cell body
Longer
Uniform diameter
How does NODDI quantify white matter structures?
Orientation dispersion Index
Neurite Density Index
Free Water Fraction
What is CT
Computed Tomography (CT) is a diagnostic imaging technique that uses X-rays and computer processing to produce detailed cross-sectional images of the body. “computed” refers to the use of computer processing to produce images. In contrast “tomography” refers to the ability to produce a three-dimensional image of a body structure by capturing multiple cross-sectional images.
What issues are CT scans used for in ER?
A CT (Computed Tomography) scan is often performed to evaluate suspected brain trauma and look for signs of injury such as:
Skull fractures
Hemorrhage (bleeding)
Contusions (bruising of the brain)
Edema (swelling of the brain)
Brain herniation
Mass lesions or tumors
Foreign objects (such as bullet fragments)
A CT scan is a non-invasive diagnostic imaging test that uses X-rays and computer processing to produce detailed images of the head and brain.
What is FDR?
The false discovery rate (FDR) isa statistical approach used in multiple hypothesis testing to correct for multiple comparisons.
What does ventral lateral mean in anatomy?
relating to both the ventral and lateral surface, or to the front and the side