Multifactorial Inheritance Flashcards
1
Q
what are the 4 fundamentals of GWAS
A
study design, genotyping, statistical analysis and validation
2
Q
haplotypes
A
3 SNPs can appear in 8 different patterns
3
Q
APOE
A
encodes a major component of the very low-density lipoprotein (VLDL) particles that remove excess blood cholesterol and carry it to the liver for processing
4
Q
people with down syndrome have how many copies of what gene?
A
3 APP
5
Q
ie. high effect common varients influencing common disease
A
age-related macular degeneration and alzheimer
