Gene Structure and Function I & II

Question 1

what guides RNA polymerase where to start

Answer 1

TATA

Question 2

what are some regulatory elements

Answer 2

enhancer or sliencer

Question 3

HDAC

Answer 3

histone deacylase. take acetylation off.

Question 4

what is used to transcribe protein coding genes

Answer 4

RNA polymerase II

Question 5

what side is transcriptional modulation on?

Answer 5

N terminus

Question 6

what side is ligand binding on?

Answer 6

C terminus

Question 7

what is the exact structure of the polyadenylation?

Answer 7

AAUAAA

Question 8

TF and how many % of genes?

Answer 8

transcription factors, 8

Question 9

what type of therapy for prostate cancer?

Answer 9

androgen antagonists

Question 10

SERM

Answer 10

selective estrogen receptor modulators

Question 11

what type of RNA is most common in mamm cell

Answer 11

rRNA

Question 12

what is miRNA made from and what does it get chopped by

Answer 12

dsRNA, Dicer

Question 13

what does telomerase add?

Answer 13

TTAGGG at 3’ end

Question 14

is RNA destroyed in translational silencing?

Answer 14

no

Question 15

trimethyl cap

Answer 15

added to 5’ following transcription

Question 16

what are the flanking nucleotides

Answer 16

GU… …AG ps. C/U-rich

Question 17

polyadenylation signal

Answer 17

AAUAAA added 3’ of mRNA