Clinical Cytogenetics Flashcards
1
Q
Nucleosomes
A
fundamental packaging unit of DNA
2
Q
p arm
A
‘petite,’ short arm
3
Q
q arm
A
long arm
4
Q
Giemsa banding
A
analysis
cultured cells arrested in metaphase (treated with colchicine)
5
Q
metacentric
A
centromere in center
6
Q
submetacentric
A
short and long arm
7
Q
acrocentric
A
have ‘very tiny short arms’
8
Q
centromere stats
A
alphoid DNA repeat unit
9
Q
telomere stats
A
beta satellite outer, tandem hexanucleotide repeats (5-TTAGGG-3)
10
Q
what stage does in cell cycle does DNA replication occur?
A
S phase
11
Q
what happens in G2?
A
cell prepares to undergo mitosis
12
Q
how many double helix are there beginning of S1?
A
1
13
Q
when does a cell have two double helices?
A
end of S
14
Q
when does recombination occur
A
meiosis 1, prophase 1
15
Q
when does reproduction arrest in female meiosis?
A
prophase 1
