Multifactorial Disorders Flashcards
1
Q
What disorders show multifactorial inheritance : congenital malformations?
A
- cleft lip/palate
- congenital hip dislocation
- congenital heart defects
- neural tube defects
- pyloric stenosis
2
Q
In alzheimer’s what does the APOE *E4 haplotype confer?
A
Increase in suscetibility
3
Q
In alzheimers what does the APOE*E2 haplotype confer?
A
protective effect