Multifactorial Disorders Flashcards

1
Q

What disorders show multifactorial inheritance : congenital malformations?

A
  • cleft lip/palate
  • congenital hip dislocation
  • congenital heart defects
  • neural tube defects
  • pyloric stenosis
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2
Q

In alzheimer’s what does the APOE *E4 haplotype confer?

A

Increase in suscetibility

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3
Q

In alzheimers what does the APOE*E2 haplotype confer?

A

protective effect

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