Muir-Torre syndrome Flashcards
1
Q
What are the symptoms of Muir-Torre Syndrome?
A
Sebaceous skin tumors accompanied by internal cancer (most common colorectal cancer)
{Oil gland skin tumors}
2
Q
What genes are involved in Muir-Torre Syndrome?
A
DNA mismatch repair gene MLH 1/2
3
Q
What is the inheritance pattern of Muir-Torre syndrome?
A
Autosomal dominant
4
Q
What is the heterozygous phenotype for Muir-Torre Syndrome?
A
A heterozygote would have Muir-Torre syndrome
