Long QT syndrome Flashcards
1
Q
What are the symptoms of Long QT syndrome?
A
Some individuals are asymptomatic
Fainting Seizure like activity Palpitations Cardiac arrest Can cause torsades de pointes (ventricular tachycardia)
2
Q
What genes are involved in Long QT syndrome?
A
KCNq1
KCNH2
*Affects genes for Na+ and K+ heart channels
3
Q
What is the inheritance pattern for Long QT syndrome?
A
Autosomal dominant
Neilson form–> autosomal recessive: very rare
4
Q
What is the phenotype for the heterozygous in Long QT syndrome?
A
Will inherited the syndrome and show symptoms
