MUE

Question 1

Inclusion criteria for MUE in the absence of histophatological diagnosis (Cornelis 2019).

Answer 1

1) Older than 6 months; 2) multiple/single/diffuse intra-axial hyperintensities on T2W; 3) pleocytosis on CSF with >50% of monocytes/lymphocytes, and 4) rule out infectious diseases

Question 2

MRI findings in dogs with histopathologically confirmed GME (Cherubini 2006)

Answer 2

T2W and FLAIR hyperintensities, grey and white matter, variable intensity on T1W and variable contrast enhancement.
+ Vasogenic oedema

Question 3

Most common MRI abnormalities in dogs with NME (Flegel 2008)

Answer 3

Asymmetrical, multifocal, parietal and occipital lobes, cortical grey and subcortical WM, loss of grey/WM demarcation + same *tensities as for MUE

Question 4

Most common MRI abnormalities in dogs with NLE (Cornelis 2019).

Answer 4

Multiple asymmetrical cerebral WM and brainstem, cystic areas of necrosis, same *tensities as for MUE

Question 5

Is it common to see meningeal enhancement and mass effect in dogs with MUE? (Cornelis 2019).

Answer 5

Uncommon (maybe more in NME).

Question 6

What is the predominant cell type in CSF samples in GME? (Cornelis 2019).

Answer 6

Lymphocytes (42% cases).

Question 7

Rerported MSTs for dogs with MUO? (Cornelis 2019)

Answer 7

28 - 1834 days.
Dogs that survived for 1 year often lived for a relatively long period beyond this.