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Neuro > Journal club > Flashcards

Journal club Flashcards

1
Q

T/F. The origin of focal seizures is limited to a single hemisphere of the brain. (Chawner 2023)

A

True.

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2
Q

Common manifestations of focal seizures include: a) head, facial or limb twitches, b) constricted pupils, c) urination/defecation, d) all of the above. (Chawner 2023)

A

a) Twitches. Also hypersalivation and dilated pupils.

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3
Q

T/F. In people, absence epilepsy manifests unilateral synchronous 3-5 Hz spike-wave. (Chawner 2023)

A

False. Bilateral.

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4
Q

Is awareness affected during focal seizures? (Chawner 2023)

A

Variable to no impairment is possible.

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5
Q

What are the definitive-intent radiotherapy options for intracranial neoplasms? (Strasberg 2024)

A

Conventionally fractionated RT (CFRT), stereotactic RT (SRT), and stereotactic radio surgery (SRS).

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6
Q

How long after RT we can see RT-induced neurotoxicity due to demyelination? (Strasberg 2024)

A

Up to about 5 months after RT.

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7
Q

T/F. For many dogs, lengthy courses of PO prednisone are avoidable after intracranial RT. (Strasberg 2024)

A

True. 84% of dogs were completely tapered off prednisone over a mean time of 41 days.

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8
Q

T/F. The rapid-tapering protocol of steroids after RT is safe but the overall survival time is shorter than with slow-taper. (Strasberg 2024)

A

False. Overall survival time was similar for the 2 groups.

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9
Q

Clinically, neurological conditions causing anisocoria include (Danciu 2024):
a) Horner syndrome
b) Idiopathic optic neuropathy
c) Pourtour du petit syndrome
d) All of the above.

A

A. Also, idiopathic OCULOMOTOR neuropathy, PourFour du petit, and asymmetrical midbrain lesions.

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10
Q

What structure in the midbrain can cause anisocoria if asymmetrically affected? (Danciu 2024)

A

Nucleus of the oculomotor nerve (parasympathetic).

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11
Q

What is the cerebellar artery most commonly affected with cerebrovascular ischemic infarcts? (Danciu 2024)

A

Rostral cerebellar artery.

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12
Q

T/F. Ischemic infarcts affecting the interposital nucleus may cause reversible mydriasis in dogs. (Danciu 2024)

A

True. Ipsilateral.

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13
Q

What are the 2 nerves that form the sciatic nerve?

A

Tibial and common peroneal nerves.

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14
Q

T/F. Axonotmesis is characterized by transection of axons and perineurial connective tissue. (Dell’Apa 2024)

A

False. That is neurotmesis.

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15
Q

The 3 types of nerve injury are: neurotmesis, …, …

A

Axonotmesis and neurapraxia.

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16
Q

Which one of the 3 types of nerve injury are associated with a worse prognosis?

A

Neurotmesis.

17
Q

What is the second most common cause of sciatic nerve injury? (Dell’Apa 2024)

A

Complications from orthopedic surgery.

18
Q

T/F. In neurapraxia, there should be no axonal damage and no signs of denervation. (Dell’Apa 2024).

A

True, especially several days after the injury.

19
Q

What is the age over which performing thoracic rads may be of clinical importance in dogs with acute T3-L3 myelopathy? (Dell’Apa 2024)

A

12 years.

20
Q

T/F. The lack of tympanic membrane alterations cannot exclude a diagnosis of OM.
(Deleporte 2024)

A

True. Sensitivity of otoendoscopy is mild.

21
Q

T/F. Within the inner ear, the medial compartment is not accessible in cats.

A
22
Q

T/F

In some studies, a negative correlation was identified between midline shift and survival time in dogs.

Guy, 2024

A

Correct.

Suñol: surgical resection of meningiomas.
Beltrán: dogs with brain trauma.

23
Q

Dogs with midline shift secondary to structural brain disease on brain MRI had a _ _ _ _ _ survival time than dogs without midline shit, regardless of diagnosis.

Guy, 2024

A

Shorter.

This conclusion is most relevant for dogs diagnosed with neoplastic and inflammatory disease.

24
Q

Dogs presenting with acute onset paraplegia with _ _ _ _ of deep pain sensation and a T2 length RATIO greater than _ are more likely to develop PMM.

Nakamoto 2024

A

Loss. Six.

T2 length ratio: length of the hyperintense intramedullary area obtained by T2W MRI, measured and compared with the length of the lumbar 2 vertebral body.

25
Q

There is a study that provides evidence that

the use of extensive hemilaminectomy and durotomy IS / IS NOT associated with increased survival rate compared with dogs that undergo HL alone.

Nakamoto, 2024

A

It is.

26
Q

Where in the nervous system is the highest virus load in Western Equine Encephalitis Virus Infection?

Carossino 2024

A

Brainstem and thalamus.

These areas are critical for diagnostic sampling.

27
Q

T/F. A territorial infarct is a subcortical infarct located at the vascular territory of an intraparenchymal deep or supperficial perforating artery.

A

False. That’s a lacunar infarct. A territorial infarct is located at the vascular territory of 1 of the main arterial supply to the brain.

Comorbidities, long-term outcome and poststroke epilepsyassociated with ischemic stroke–A multicenter observationalstudy of 125 dogs

28
Q

T/F. Arterial spin labeling is a noninvasive MRI perfusion technique for quantitative evaluation of cerebral blood flow.

Exploring brain perfusion in dogs with MUO

A

True.

29
Q

T/F. Dogs with MUO can have focal brain perfusion alterations and global brain hypoperfusion.

A

True, based on arterial spin labeling.

Exploring brain perfusion in dogs with meningoencephalitis ofunknown origin:

30
Q

T/F. Arterial spin labeling can predict prognosis in dogs with MUO.

A

False, it failed to predict prognosis.

Exploring brain perfusion in dogs with meningoencephalitis ofunknown origin.

31
Q

Based on the study by Dr. Steffen et al, non-ambulatory dogs with thoracolumbar IVDD that received surgical decompression and local application of methylpred achieved ambulation in how many days?

Effect of local epidural application of methylprednisoloneacetate on time to ambulation in non-ambulatory dogs withthoracolumbar intervertebral disc disease: A prospectiverandomised, blinded control trial

A

Within a median of 3 days.

Compared to 7 days in the control group.

32
Q

T/F. Local application of methylrednisolone acetate in combination with surgical decompression may lead to faster ambulation in non-ambulatory dogs with thoracolumbar IVDD.

Effect of local epidural application of methylprednisoloneacetate on time to ambulation in non-ambulatory dogs withthoracolumbar intervertebral disc disease: A prospectiverandomised, blinded control trial

A

True.

Anti-inflammatory properties of steroids may play a role in mitigating the inflammatory response and promoting faster recovery of SC conduction.

33
Q
A

Neuro (16 decks)

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