mucosal infections Flashcards
what is used to treat hsv 1
acyclovir
what causes herpetic gingivostomatitis
hsv
where does hsv lie latent in
neurons
how does recurrent hsv manifest
herpes labialis/cold sores. many recurrences asymptomatic, viral shedding
what are the primary and secondary infections of hhv3
primary infection is varicella. in childhood. asymptomatic. widespread cutaneous lesions
secondary infection is herpes zoster. dermatomal rash that does not cross midline, intense inflammation and severe pain along single dermatome
patient presents with rash that does not cross midline
herpes zoster hhv3
which virus remains latent in b lymphocytes
hhv 4 ebv
clinical presentations of hhv4
asymptomatic if acquired in childhood. infectious mononucleosis in adulthood.
OHL (bilateral, cannot be removed)
NPC
Hodgkins lymphoma
no vaccine no specific antivirals
how does cmv clinically present
symptomless in healthy patient. occasional mononucleosis like symptoms.
significant morbidity in immunosuppressed. pneumonitis, gastroenteritis in transplant patients. cytomegalic inclusion disease in neonates
which hhv causes kaposi sarcoma
hhv8
clinical manifestation sof coxsackie
herpangima, hfmd
which hpv high oncogenic potential
16, 18, 31
Whar cancers are hpv linked to
cervical and oropharyngeal
what oral lesions are associated with HIV
candidiasis
OHL
kaposi sarcoma (europians)
non hodgkins lymphoma (asians): necrotic mass
linear gingival erythema: red linear band at marginal gingiva with spontaneous bleeding not associated with poor oh
NUG at interdental papilla, spread along gingival margins
what is the gold standard test for hiv
western blot testing for antibodies (p24 is sensitive but not specific, test weeks after exposure)