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1 NAS > MTM AP04 - connective tissue > Flashcards

MTM AP04 - connective tissue Flashcards

1
Q

What are the 3 connective tissue types?

A

Loose connective tissue
Dense irregular tissue
Dense regular tissue

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2
Q

Where is loose connective tissue?

A

underneath the epidermis, around organs, blood vessels, and nerves

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3
Q

What is within loose connective tissue?

A

fibroblasts
elastic fibres
mast cells
macrophage

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4
Q

What do fibroblasts do?

A

secrete proteoglycans and collagen

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5
Q

What are mast cells?

A

Cells filled with basophilic secretory granules

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6
Q

What do mast cells secrete?

A

heparin (anticoagulant)

Histamine (promotes smooth muscle contraction)

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7
Q

How do macrophage react to India ink?

A

They absorb it, as it is a foreign substance

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8
Q

What is the dominant cell type in dense irregular tissue?

A

Fibroblasts

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9
Q

Where is dense irregular tissue found?

A

In the reticular dermis

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10
Q

What advantage does the irregular nature of DIT offer?

A

It is very strong, so can resist forces in multiple directions

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11
Q

What does DIT contain more of than dense regular tissue?

A

Ground substance, as there is more friction between collagen fibres

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12
Q

What types of fibre are found in DRT?

A

White collagen fibres or yellow elastin fibres

They can then be either in chord or sheath arrangement

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13
Q

What helps with strength in DRT

A

Uniparallel fibres type I collagen

Fibroblasts

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14
Q

What are elastic fibres made of?

A

Elastin and microfibrils like fibrin

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15
Q

Why do adipocytes show up as white?

A

Under Masson’s trichrome, the fat dissolved, and the nucleus is compressed to one side anyway

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16
Q

What is brown fat?

A

Multilocular fat
elliptical and smaller cells, with many lipid droplets, more mitochondria, and an oval nucleus
Iron in mitochondria makes them brown

17
Q

What is white fat?

A

Spherical and have a single lipid droplet, with a flattened peripheral nucleus

18
Q

What is EDS?

A

Ehler’s Danlos syndrome
caused by an abnormality of collagen arrangement
hypermobile is far less serious than vascular EDS

19
Q

What two main substances do all connective tissue contain?

A 
fibres
Ground substance (contains glycoaminoglycans, strongly hydrophilic)
20
Q

What are fibrocytes?

A

quiescent fibroblasts

21
Q

What is non-specialised loose connective tissue?

A

Areolar

22
Q

What is mucosa comprised of?

A

epithelia
basement membrane
lamina propria

1 NAS (12 decks)

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