MSRA: Breast Disease Flashcards
What is the most common type of breast cancer?
Invasive ductal
What is the use of radiotherapy in breast cancer?
Following wide local excision
Whole breast radiotherapy to reduce disease recurrence
Which women with a family history can be referred?
Family member age of diagnosis less than 40
Family member has bilateral breast cancer
Or breast cancer in a male relative
(The women themselves do not have to have any symptoms of breast disease, but should be referred to secondary care if positive family history)
Refer if 1st/2nd degree relative with breast AND 1st/2nd degree relative with ovarian, both at any age
What is the breast cancer screening programme?
50-70 years
Mammogram every 3 years (this is not th same as triple assessment)
Which antibiotic is used in the treatment of mastitis?
Flucloxacillin
What are the key features of duct papilloma?
Local areas of epithelial proliferation
May present with blood stained discharge
What are the key features of duct ectasia?
Tender lump around the areola with green nipple discharge
What are the NICE 2ww referral criteria?
30+ with unexplained breast lump
50+ with nipple changes
Consider if 30+ with unexplained lump in axilla
What is the mechanism of action of Tamoxifen?
Selective oestrogen receptor modulator
What options are avaialble for women with oestrogen receptor positive breast cancer?
If pre-menopausal -> Tamoxifen
If post-menopausal -> Aromatase inhibitors
What investigation is needed for women taking Aromatase inhibitors?
DEXA scan due to risk of osteoporosis
What are the side effects of Tamoxifen?
Hot flushes ** most common **
VTE
Endometrial cancer
What are the key features of a breast cyst?
Fluid-filled cyst
Fluctuant
Management = aspiration
What are the key features of fibroadenoma?
Non-tender, rubbery, mobile, discrete solid firm lump
If >3cm then surgical excision
