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B > MSK/Rheum > Flashcards

MSK/Rheum Flashcards

1
Q

Anti CCP

A

RA

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2
Q

Anti dsDNA

A

SLE

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3
Q

Anti-Ro, anti-La

A

Sjogren’s syndrome, SLE

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4
Q

Serum ACE

A

Sarcoidosis

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5
Q

Anti-centromere antibody

A

Limited scleroderma

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6
Q

Anti Jo-1

A

Polymyositis with lung involvement (may be dermatomyositis)

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7
Q

Negatively birefringent crystals under polarised light (needle-like)

A

Gout

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8
Q

Anti-cardiolipin

A

SLE + APLS

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9
Q

Heliotropic rash and Gottron’s papules

A

Dermatomyositis

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10
Q

Headache, raised ESR, trouble getting out of chair

A

GCA with polymyalgia rheumatica

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11
Q

Anti-Smith

A

SLE

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12
Q

Global loss of joint motion with stiffness

A

Adhesive capsulitis

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13
Q

Anti-SCL-70 (anti topoisomerase)

A

Systemic sclerosis

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14
Q

Polyarthritis, conjunctivitis, urethritis

A

Reactive arthritis (can’t see, can’t pee, can’t climb a tree)

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15
Q

Positively birefringent crystals under polarised light

A

Pseudogout

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16
Q

IgA with purpuic rash

A

Henoch-Schonlein purpura

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17
Q

Anti-GBM

A

Goodpastures

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18
Q

Shawl’s sign

A

Dermatomyositis

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19
Q

Tensilon test

A

Myasthenia gravis

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20
Q

Wrist pain on forced thumb adduction and flexion

A

De Quervain’s tenosynovitis

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21
Q

Prominent and tender tibial tubercle

A

Osgood-Schlatter’s disease

22
Q

Hypopigmentation + autoimmune disease

A

Vitiligo

23
Q

Arthalgia + uveitis + orogenital ulcers

A

Behcet’s disease

24
Q

Positive Schirmer’s

A

Sjogren’s syndrome

25
Q

Question mark posture

A

Ankylosing spondylitis

26
Q

Arthralgia + reduced lung volumes

A

SLE

27
Q

Obese boy - hip flexed, abducted and externally rotated

A

Slipped femoral epiphysis

28
Q

Round-shouldered

A

Scheuermann’s disease

29
Q

Gold standard for diagnosing Sjogren’s

A

Salivary gland biopsy (lymphocytic infiltrate)

30
Q

Investigations for pathological fracture (2)

A
  1. DEXA (OA)

2. CMP/Bence-Jones (myeloma)

31
Q

Pencil in cup

A

Psoriasis

32
Q

RA + splenomegaly

A

Felty’s syndrome

33
Q

Contortionist

A

Ehlers-Danlos syndrome

34
Q

Back pain + TB

A

Pott’s disease of the spine

35
Q

Increased trabecular pattern and cortical thinking of the right hemipelvis with loss of joint space and osteophyte formation of the right hip

A

Paget’s disease of bone

36
Q

PAS positive macrophages in intestinal biopsies

A

Whipple’s disease

37
Q

Absent callus

A

Delayed union

38
Q

Painful shoulder after seizure

A

Posterior dislocation

39
Q

Gait seen in proximal myopathy

A

Waddling gait

40
Q

Twisting injury

A

Meniscal tear

41
Q

DRUG SE: irreversible retinopathy and alopecia

A

Hydroxychloroquine

42
Q

DRUG SE: gum hypertrophy

A

Ciclosporin

Others: phenytoin, calcium channel blockers

43
Q

DRUG SE: exfoliative dermatitis

A

Gold

44
Q

DRUG SE: reversible oligospermia

A

Sulfasalazine

45
Q

DRUG SE: pulmonary and hepatic fibrosis

A

Methotrexate

46
Q

DRUG SE: nephrotic syndrome

A

Gold

47
Q

Cancer associated with Paget’s disease of bone

A

Osteosarcoma

48
Q

Posterior fat pad sign

A

Radial head fracture

49
Q

Back pain + anterior uveitis

A

Ank spond

50
Q

DRUG: scleroderma crisis

A

ACE inhibitor

B (13 decks)

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