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B > Haem > Flashcards

Haem Flashcards

1
Q

Schilling test

A

B12

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2
Q

Pepperport skull (lytic lesions)

A

MM, hyperparathyroidism

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3
Q

Pepperport skull (lytic lesions)

A

MM, hyperparathyroidism

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4
Q

Normocytic anaemia 6 weeks after flucloxacillin therapy

A

Autoimmune haemolytic anaemia

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5
Q

Osteopenia/lytic lesions + hypercalcaemia + rouleaux

A

Multiple myeloma

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6
Q

Target cells

A

Thalassaemia

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7
Q

Stomatocytes

A

Thalassaemia

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8
Q

Hypersegmented neutrophils

A

Megaloblastic anaemia

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9
Q

Heinz bodies and bite cells

A

G6PDH deficiency or pyruvate kinase deficiency

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10
Q

Jaundice after eating fava beans/ciprofloxacin/sulphonamide

A

G6PDH deficiency

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11
Q

Spherocytes

A

Hereditary or autoimmune haemolytic anaemia

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12
Q

Schistocytes

A

Microangiopathy (e.g. DIC) or intravascular prostheses

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13
Q

Haemolytic anaemia and aplastic anaemia after parvovirus infection

A

Sickle cell anaemia

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14
Q

Acanthocytes

A

Severe liver disease (hyperlipidaemia)

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15
Q

Cold-reacting antibodies (4)

A 
HIV
Mycoplasma
EBV
Lymphoma
13
Reticulocytes

Haemolysis

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16
Q

Anaemia and peripheral neuropathy

A

B12 deficiency

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17
Q

Young boy with swollen knee

A

Haemophilia

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18
Q

Tissue death and bleeding in a septic patient

A

DIC

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19
Q

Jaundice and kidney failure after diarrhoea in child

A

HUS

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20
Q

FTL3 mutation

A

AML

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21
Q

Marrow >20% blasts

A

AML, ALL

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22
Q

TEL-AML1 mutation

A

ALL

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23
Q

Philadelphia chromosome/BCR-ABl/9 to 22

A

CML

24
Q

Reed-Sternberg cells

A

Hodgkin lymphoma

25
Q

Facial lymphoma caused by EBV

A

Burkitt’s lymphoma

26
Q

Starry sky appearance

A

Burkitt’s lymphoma

27
Q

Mesenteric lymphadenopathy

A

Non-Hodgkin lymphoma

28
Q

CD 19, 20, 21, 23, 32, 25, 40

A

B cell neoplasm

29
Q

5q mutation

A

Myelodysplasia

30
Q

5q mutation

A

Myelodysplaia

31
Q

Replacement of stem cells with fat in bone marrow

A

Aplastic anaemia

32
Q

JAK2 mutation

A

Myeloproliferative disorder (PV, ET, PMF)

33
Q

JAK2 mutation

A

Myeloproflierative disorder (PV, ET, PMF)

34
Q

Pruritus, red skin and headache

A

PRV

35
Q

Pruritis, red skin and headache

A

PRV

36
Q

Treat with Glivec (imatinib)

A

CML

37
Q

Lupus anticoagulant, anticardiolipin, anti-B2-glycoprotein-I, anti-ApOH

A

Antiphospholipid syndrome

38
Q

Lupus anticoagulant, anti-cariolipin, anti-B2-glycoprotein-I, anti-ApOH

A

Antiphospholipid sydrome

39
Q

Pancytopenia, thrombosis, haemolytic anaemia and positive Ham test What’s the treatment?

A

Paroxysmal nocturnal haematuria Eculizumab

40
Q

Hair-on-end skull, frontal and parietal bossing

A

Beta thalassaemia

41
Q

Most common complication in multiple myeloma

A

Fractures

42
Q

Iron-related complications of myelodysplastic diseases

A

Iron overload and refractory anaemia

43
Q

Thrombosis 4 days after heparin

A

Heparin-induced thrombocytopenia

44
Q

Afro-Caribbean

A

Sickle cell

45
Q

Abdo pain + headaches after a respiratory infection

A

Sickle cell crisis

46
Q

DRUG SE: folate deficiency (6)

A 
Sulfasalazine
Trimethoprim
Anticonvulsants
Methotrexate
Metformin
OCP
45
Burr cells

Uraemia

47
Q

Howell-Jolly bodies

A

Hyposplenism

48
Q

Lymphoplasmacytoid cells

A

Waldenstrom’s macroglobulinemia

49
Q

Osmotic fragility test

A

Hereditary spherocytosis

50
Q

Cancer associated with pernicious anaemia

A

Gastric

51
Q

Renal failure + light chains

A

Multiple myeloma

52
Q

RA + splenomegaly + pancytopenia

A

Felty’s syndrome

53
Q

Hepatosplenomegaly + pigmentation + anaemia + pathological fractures

A

Gaucher’s syndrome

54
Q

Non-existent coagulation factor

A

VI

55
Q

Monoclonal spikes

A

Multiple myeloma, MGUS

56
Q

Bence-Jones proteins

A

Multiple myeloma

B (13 decks)

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