MSK: antibodies Flashcards

1
Q

acetylcholine receptor ab’s

A

myasthenia gravis

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2
Q

Beta-2 glycoprotein 1 ab’s

A

antiphospholipid syndrome

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3
Q

cardiolipin ab’s

A

antiphospholipid syndrome

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4
Q

centromere ab’s

A

CREST syndrome (Limited)

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5
Q

cyclic citrullinated peptide (protein)-ccp

A

specific for rheumatoid arthritis

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6
Q

double-stranded DNA ab’s

A

SLE

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7
Q

endomysial ab’s

A

celiac disease

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8
Q

glomerular basement membrane ab’s

A

Goodpasture’s syndrome

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9
Q

Histone ab’s

A

Drug-induced lupus

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10
Q

Jo-1 ab’s

A

polymyositis and dermatomyositis

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11
Q

LA (SS-B) ab’s

A

Sjrogen syndrome

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12
Q

lupus anticoagulant ab’s

A

antiphospholipid syndrome

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13
Q

Mi-2 ab’s

A

dermatomyositis

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14
Q

mitochondrial ab’s

A

primary biliary cirrhosis

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15
Q

muscle specific receptor tyrosine kinase (MUSK) ab’s

A

myasthenia gravis

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16
Q

P-ANCA

A

-Microscopic polyangiitis
-Churg Strauss
-Ulcerative colitis
-Primary Sclerosing Cholangitis

17
Q

Rheumatoid factor ab’s

A

Rheumatoid arthritis

18
Q

Ribonucleoprotein (RNP) ab’s

A

Mixed Connective Tissue disease, SLE

19
Q

Ro (SS-A) ab’s

A

Sjrogen syndrome, SLE

20
Q

Saccharomyces cerevisiae ab’s

A

Crohn’s disease

21
Q

SCL-70 (topoisomerase) ab’s

A

Diffuse Systemic Sclerosis (Scleroderma)

22
Q

Signal recognition protein (SRP) ab’s

A

polymyositis

23
Q

smith ab’s

A

SLE

24
Q

smooth muscle ab’s

A

autoimmune hepatitis

25
Q

thyroglobulin ab’s

A

hashimoto’s thyroiditis, autoimmune thyroiditis

26
Q

thyroid peroxidase (TPO) ab’s

A

hashimoto’s thyroiditis, autoimmune thyroiditis

27
Q

topoisomerase (SCL-70) ab’s

A

Diffuse Systemic Sclerosis (Scleroderma)

28
Q

transglutiminase ab’s

A

celiac disease, dermatitis herpetiformis

29
Q

TSH (thyrotropin) receptor ab’s

A

Graves’ disease

30
Q

voltage-gated calcium channel ab’s

A

Lambert-Eaton Syndrome

31
Q

C-ANCA

A

granulomatosis with polyangiitis (GPA)