CARDIO Flashcards
MC valve affected by infective endocarditis
Mitral (tricuspid if IVDA)
MC organism to cause acute infective endocarditis
staph aureus (esp IVDA)
MC organism to cause subacute infective endocarditis
streptococcus viridans
MC organism in early prosthetic valve endocarditis
staph epidermidis
Endocarditis in men >50 years old with recent GI or GU procedure, likely caused by this organism
enterococcus
Suspect these organisms in pt with endocarditis and negative bcx
HACEK organisms
Haemophilus aphrophilus
Actinobacillus
Cardiobacterium hominis
Eikenella corrodens
Kingella kingae
Dx for endocarditis
Modified Duke criteria
Rq. +2 major, +1 major and +3 minor, or +5 minor
–major: pos bcx, pos echo
–minor: predisposing condition (recent procedure, ivda, etc), fever, vascular or embolic phenomena (janeway lesions, septic arterial or pulmonary embolic, etc), immunologic phenomena (Osler’s node, Roth spots, +RF, acute glomerulonephritis), +BCx or +TTE not meeting major criteria
Tx for endocarditis
anti-staphylococcal pcn (nafcillin or oxacillin) and ceftriaxone or gentamicin x4-6 weeks
Tx for prosthetic endocarditis
Vancomycin, gentamicin, and rifampin x4-6 weeks
Endocarditis ppx indications
- predisposing cardiac condition (prosthetic valve, h/o endocarditis, congenital heart disease, cardiac valvulopathy in heart transplant pt) AND 2. Routine dental, respiratory, or skin procedure (includes I&D)
Endocarditis ppx tx
amoxicillin 2g 30 min preop (clinda 600mg if allergic)
2 MC causes of pericarditis
idiopathic and viral (enterovirus, coxsackie virus)
Triad in Dressler syndrome:
post-MI pericarditis, fever, pleural effusion
electrical alternans is seen in this condition
pericardial effusion
(alternating QRS complex amplitude)
Dx of cardiac tamponade:
TTE w/ pericardial effusion and diastolic collapse of chambers
Tx of cardiac tamponade:
immediate pericardiocentesis
Dx for constrictive pericarditis:
TTE w/ pericardial thickening or calcifications (CT scan or MRI more sensitive than TTE)
pericardial knock may be heard in this condition
constrictive pericarditis
Tx for constrictive pericarditis:
sxs: diuretics
definitive mgmt: pericardiectomy
MC valvular disease
aortic stenosis
MC innocent physiologic murmur
still murmur
MC continuous benign murmur
cervical venous hum
Congenital heart disease that can lead to paradoxical embolic or cryptogenic strokes
PFO, ASD
MC type of ASD
ostium secundum
congenital narrowing of the aortic lumen at the distal arch, often associated w/ bicuspid aortic valve
COA
MC cyanotic congenital heart disease
TOF
“blue baby syndrome”
MC cyanotic congenital heart disease presenting in neonatal period
TOGA
MC type of congenital heart disease in childhood
VSD
MC type of VSD
perimembraneous
Most common RF for CAD
DM (considered anginal equivalent)
Most common modifiable RF for CAD
smoking
CI to myocardial perfusion imaging
severe bronchospastic disease
MC cause of MI
atherosclerosis
Drug of choice for HTN in post-MI
ACEi, BB
Drug of choice for HTN in HF
ACEi, ARB, BB
Drug of choice for HTN in BPH
alpha1 blockers (prazosin, terazosin, doxazosin)
Drug of choice for HTN in DM
ACEi, ARB
Drug of choice for HTN in AA
TZDs, CCB
Drug of choice for HTN in gout
CCB
Drug of choice for HTN with concurrent afib/flutter
BB, CCB
CI to CCB
CHF and 2nd/3rd AVB
CI to BB
CHF and 2nd/3rd AVB (nonselective CI in asthma/copd)
MC cause of syncope
vasovagal (includes prodomal phase)
Beck’s triad is seen in this condition
pericardial tamponade (increased JVP, hypotension, muffled heart sounds)
Define SIRS:
Rq 2/4:
1- Temperature (>38 or <36)
2- Pulse >90
3- RR > 20 or PaCO2 <32mmHg
4- WBC >12k or <4k
Define sepsis:
SIRS + source of infx (often lactate >4mmol/L)
Define severe sepsis:
sepsis + end organ damage
Define septic shock:
sepsis + refractory hypotension despite fluids (SBP <90, MAP <65, or drop in SBP 40mmHg from baseline)
only major type of shock associated with increased cardiac output
distributive
Best meds to lower LDL
Statins
Best meds to lower Tg
Fibrates
Best meds to increase HDL
Niacin
MC cause of ventricular tachycardia and fibrillation
ischemic disease
Define CHADS2-VAS:
CHF
HTN
Age > 75 (+2)
DM
Stroke (+2)
Vascular (prior MI, PAD)
Age >65
Sex (female)
sinus arrest w/ alternating paroxysms of atrial tachyarrhythmias and bradyarrhythmias
sick sinus syndrome (Brady-tachy syndrome)
Initiate statin in patients with: (5)
- Age 40-75 yo with diabetes
- Age 40-75 yo with >7.5% CVD risk for MI or CVA in 10 years
- Age >21 with LDL >190
- Age <19 yo with fam hypercholesteremia
- Clinical CVD
MC cause of primary HTN
idiopathic
MC cause of secondary HTN
renovascular
MC cause of ESRD
DM