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Asem > MSK and SKin > Flashcards

MSK and SKin Flashcards

1
Q

LEMS has _muscle weakness (first) + _ symptom and _ with exercise(as opposed to MG)

A

LEMS has proximal muscle weakness (first) + autonomic symtoms and normalizes with exercise(as opposed to MG)

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2
Q

Pathogenesis of RA is via macrophage _= eternercept targets.

A

Pathogenesis of RA is via macrophage TNF(a)= eternercept targets.

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3
Q

Goodpastures vrs contact dermatis = type _ vrs type _

A

Wound Healing: contracture due to inc MMP + myofibroblasts activity

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4
Q

Ant. view of knee: ACL/PCL attach _ + _ femur condyle/

A

Ant. view of knee: ACL/PCL attach ant + lat femur condyle/ post + medial femur condyle

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5
Q

obturator artery/ medial circumflex important for child/adult because /

A

obturator artery/ medial circumflex important for child/adult because epiphyseal growth plate in head /main blood supply to femoral neck

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6
Q

Paget disease labs: all normal except _

A

Paget disease: all normal except Alk phosphotase

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7
Q

Drug induced lupus eythematosus(DILE): _antibodies more specific than anti-dsDNA -> presents in slow acetylators( procainamide)

A

Drug induced lupus eythematosus(DILE): Anti-histone antibodies more specific than anti-dsDNA -> presents in slow acetylators( procainamide)

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8
Q

Dermatomyositis has _ inflammation

A

Dermatomyositis has perimysial inflammation(because skin affected too)

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9
Q

anti-_ for crest vrs dna_ for SCL

A

anti-centromere( c for crest vrs dna topoisomerase for SCL)

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10
Q
  1. Alkaptouria vrs homocyteinuria=
A
  1. Alkaptouria/ homocyteinuria= homogenistic oxidase def/ methinine or cytathione syntase problem -> systemic symptoms
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11
Q

IL-1 and TNF-A are inflammatory cytokines(cox-_ is induced l):
celeximab ( mech selectivity inhibits cox-_)

infliximab inhib _

A

IL-1 and TNF-A are inflammatory cytokines(cox-2 is induced vrs cox-1 constituitional): celeximab ( mech selectivity inhibits cox-2)
infliximab inhib TNFa

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12
Q

Hematogenous osteomyelitis: adults/children = where -> sequestrum _ by involcrum (?)

Vertebral osteomyeliitis: recent _ predispose , _ of spine is best for imagining

Analgesics and close follow up for _issues

A

Hematogenous osteomyelitis: adults/children = vetebral/metaphysis -> sequestrum surrounded by involcrum = necrotic bone + overlying bone

Vertebral osteomyeliitis: recent endocarditis/bacteremia( staph) , MRI of spine is best
Analgesics and close follow up for MSK issues

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13
Q

_ :systemic sysmptoms + cervical _laxation( spares hips and lubosacral joints) + anti CCRP

A

RA: systemic sysmptoms + cervical sublaxation( spares hips and lubosacral joints) + anti CCRP

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14
Q

Only _ is intracellular

A

11 Only K is intracellular

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15
Q

Dermatomyositis compared to polymyo?

A

Dermatomyositis with malignancy(both with intersititial lung diseae)

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16
Q

Presentation of Strep pyo diseases do not have to be _most likely exclusive: RPGN vrs rheumatic disease

A
  1. Presentation of Strep pyo diseases do not have to be concurrent most likely exclusive: RPGN vrs rheumatic disease
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17
Q

anti _= anti-TRNA synthetase

A

anti-smooth muscle/ anti mitochondrial = autoimmune hepatitis/ PBColangitis,
anti jo= anti-TRNA synthetase

18
Q 
ant. cruciate sticks to _ of femur
menisci does?
pec anserine(gts):
A
  1. ant. cruciate sticks to ant & lat of femur pca is post & medial
    menisci is shock absorber
    pec anserine(gts): sat, semi tend, gracialis
19
Q

WHat does not change? in sacromere

A

Muscle: HI = thick/thin change A= doesn’t change

20
Q

Cutaneous small vessel vasculitis: leukocytoclastic(fragmented ) + lower leg nonblanching _ due to

Urticaria: transient, raised, _ due to meds; type 3 hypersensitivty

A

Cutaneous small vessel vasculitis:leukocytoclastic(gragmented neutrophils) + lower leg nonblanching purpura due to medications
Urticaria: transient, riased, blanchable due to meds; type 3 hypersensitivty

21
Q

_ = bacitran

A

PYR = bacitran

22
Q
  1. Greater sciatic and sacro spine in sacrium are _

spinal stenosis is _dependent symptoms

A
  1. Greater sciatic and sacro spine in sacrium are above

spinal stenosis is posture dependent symptoms

23
Q

Methotrexate(2l /hydroxychloroquine( _)/ minocycline ( _) cause = adverse effects

A

Methotrexate(lung + liver) /hydroxychloroquine( eye)/ minocycline ( dermatitis) cause = adverse effects

24
Q

Leukocyte adhesion deficieny due to lack of CD_

A

Leukocyte adhesion deficieny due to lack of CD18

25
Q

golgi tendon organ vrs muscle spindle system ?

A

golgi tendon organ vrs muscle spindle system regulate force/ lenght

26
Q

PPI’s lansoprazole can cause _, _ infect

colchicine adverse effects: _ upset

A

diltiazem, Escitalopram
PPI’s lansoprazole can cause osteoporosis
colchicine adverse effects: GI upset(diarrhea)

27
Q

Acne presents as ?

_ used is a know cause in atlethes

A

Acne presents as comedomal eruptions; anabolic steroid used is a know cause in atlethes

28
Q

Acne is inflammatory disorder of _ follicles with _keratinization of follicles->sebaceous gland _>sebum secretion-> by propion bacteria

A

Acne is inflammatory disorder of pilosebaceous follicles with hyperkeratinization of follicles->sebaceous gland enlargement>increased sebum secretion->colonization by propion bacteria

29
Q

treatment for psoriasis: topical _ & vit _ which inhib cell proliferation & stimulate differentiation

A

treatment for psoriasis: topical coticosteriods & vit D which inhib cell proliferation & stimulate differentiation

30
Q

compound nevi is in both _ so _ but not melanoma

A

compound nevi is in both epidermis & dermis so invasive but not melanoma

31
Q

acne risk factors: _(steroid type) pilosebaceous glands obstruction by oil based products, _irritation of follicules, _ paticipation

A

acne risk factors: androgens, pilosebaceous glands obstruction by oil based products, mechanical irritation of follicules, sports paticipation

32
Q

Actinic keratosis different from psoriasis on picture how?

A

scaly erythematous lesions with keratinocyte atypia, hyperkeratosis and parakeratosis with sand-paper like texture vrs thick white silvery scale

33
Q

Vitiligo is due to _of epidermal melanocytes, looks like?

A

Vitiligo is due to loss of epidermal melanocytes, looks like?

34
Q

How does sports participation trigger acne?

A

How does sports participation trigger acne: via used of tight-fitting clothing and protective gear

35
Q

Scabies: _ infection with excoriations and burrows _; presents with impaired _-mediated immunity; treat with _ or ivermectin

A

Scabies: mite infection with excoriations and burrows rash; presents with impaired cell-mediated immunity; treat with permethrin or ivermectin

36
Q

Foreign bodies elicit _ response.

A

Foreign bodies elicit granulomatous response.

37
Q

Supracondylar fractures may damages 3 thing under what conditions? lateral/medial displacement of proximal fracture seg?

A

Supracondylar fractures may damages 3 thing under what conditions? lateral/medial displacement of proximal fracture seg? Radial nerve/median nerve & brachial artery

38
Q

Another name for flexure retinaculum?

A

Another name for flexure retinaculum? Transverse carpal ligament

39
Q

Osteomyelitis? Bone infection. Most common bacteria 3 (child, sickle cell, pot, diabetes, impaired mobility, surgery)?

A

Osteomyelitis? Bone infection. Most common bacteria (child, sickle cell, pot, diabetes, impaired mobility, surgery)? staph ->strep, salmonella

40
Q

Direct inguinal due to weakness of what ? In what triangle? Borders

A

Direct inguinal due to weakness of what ? In what triangle? Borders
Transversalis fascia, hasselbach, rectus abdominus& epigastric vessels( med & lat)

41
Q

MM on BM aspirate?

>_Plasma cell with _nuclear paleness(golgi) and clockface

A

MM on BM aspirate?

>10% Plasma cell with perinuclear palenss(golgi) and clockface

42
Q

Psoa is where?

A

Psoa is here? Psoas is at the veterbra, illacus is at the illac crest.

Asem (9 decks)

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