MSK Flashcards
Kehr’s sign?
Referred L shoulder pain from splenic rupture
Cullen sign?
Periumbilical ecchymosis from pancreatitis
Grey Turner’s sign
Ecchymosis of the flank from pancreatitis
Lisker’s Sign
Tibial bone tenderness from DVT
Blumberg’s sign
Abdominal rebound tenderness from peritonitis
Cartilage like cells in bone biopsy
Chondrosarcoma
Define osteomalacia
failure to calcify bone matrix
well-calcified erratically shaped bony spicules with grouped cement lines, which form a mosaic pattern
Paget’s Disease
Most common pediatric bone tumor?
Osteosarcoma
Most common site of metastasis of osteosarcoma?
The lungs
Initial tx for Ankylosing spondylitis
NSAID’s
Why not to give NSAID’s to patients with renal compromise?
non-steroidal medications block prostaglandin-mediated vascular relaxation, effectively vasoconstricting and decreasing glomerular filtration rate and renal function
Russell bodies?
Accumulations of Immunoglobulin (protein) in cells
Autoantibodies to Double Stranded DNA
Diagnostic for SLE
Oligoclonal antibodies
Diagnostic for MS (80-90%)
Antineuronal antibodies
Diagnostic for paraneoplastic syndromes
Serum marker for RA?
IgM for Rheumatoid Factor
Hypogammaglobinemia
Scleroderma
CREST syndrome
Calcinosis Raynaud's Phenomenon Esophageal Dysmotility Sclerodactyly Telangiectasia
Elevated Calcium Phosphokinase levels
Duchene Muscular Dystrophy
Brown Sequard’s Syndrome
Spinal lesion with 3 biggies (MVP)
- Motor deficit ipsilateral side
- Vibratory loss ipsilateral side
- Pain and temperature deficit contralateral side
proximal muscle weakness
Polymyalgia rheumatica
Diagnostic study for septic arthritis?
Fluid with WBC > 50,000 predominantly neutrophils
Raynaud’s disease vs phenomenon
Disease, <30 years old, primary condition
Phenomenon >30 years old, secondary to other condition
Pes anserine bursitis
Inflammation of the bursa inferior to the knee.
most common elbow fx ages 2-12
subcondylar fracture
Pott Disease?
TB of the spine
Pain and swelling of the DIP’s and SI joints. Also “sausage fingers”
Psoriatic arthritis
Medial rotation ONLY of the humerus
Subscapularis
Sunburst appearance on radiograph of bone lesion
Osteosarcoma
most common sites for osteosarcoma?
- Distal femur
- Proximal tibia
- Proximal humerus
Labs for suspected osteosarcoma?
LDH - High LDH without mets have poorer outcomes
Alk Phos - Elevated level indicates risk of lung mets
Simple cyst of bone
Most common in children, proximal femur and proximal humerus
- Usually present with pathologic fracture
- Mostly fibrous, thin walled with occasional giant cells
Treatment of simple cyst of the bone?
- Aspiration and injection of methylpredisone
- If failed surgery
Initial finding of osteoarthritis in regard to cartilage?
Thickening of the cartilage
Gamekeeper’s thumb
Ulnar collateral ligament, laxity on Abduction
Risk factors for AVN?
CAT ASS
- Coagulopathies
- Alcoholism
- Trauma
- Autoimmune disease (SLE, RA)
- Sickle Cell Disease
- Steroid use
Duration of ABX for osteomyelitis?
4-6 weeks
Findings for Kawasaki Disease
Mucocutaneous lymph node syndrome includes
- Fever
- Conjuncitval and oral erythema
- Edema of hands and feet
- Erythema on palms and soles
- Skin rash often (desquamation)
- Cervical lymphadenopathy
Expected recovery time for adhesive capsulitis
1-2 years, PT may help
Sarcopenia?
Normal muscle atrophy of aging
The reason estrogen protects against bone wasting
Estrogen inhibits osteoblast apoptosis and stimulates osteoclast apoptosis
Gower’s Sign
Having to climb up on oneself to stand. Indicates Duchene Muscular Dystrophy
