MSK 19 Flashcards
What is Osteomyelitis?
An infection of the bone
Osteomyelitis can be acute or chronic?
both
Chronic osteomyelitis can leads to?
bone necrosis and subsequent chronic infections
What are the types of osteomyelitis?
2
Hematogenous.
Contiguous.
what is Hematogenous osteomyelitis?
infection originate from blood then goes to bone
What is contiguous osteomyelitis?
by touching
i) Without muscular sufficiency
ii) With vascular sufficiency
Haematogenous osteomyelitis in “children” causes which bone?
Femur, Tibia
Haematogenous osteomyelitis in “elderly” causes which bone?
Vertebra
What is Contiguous osteomyelitis
caused by polymicrobials or multiple pathogen
vascular insufficiency common for which patients?
Vascular insufficiency=trouble coming back blood from leg to heart.
diabetics & PVD (peripheral vascular disease)
What is the common pathogens cause Osteomyelitis?
Staphylococcus Aureus
What is Coagulase negative staphylococci?
Staphylococcus epiderma-titis (which means staph bacteria that usually leaves on your skin)
Risk factors for osteomyelitis?
Poor vascularity Immunocompromised IV drug users Catheters users Sickle cell disease Trauma
What is the Diagnosis of osteomyelitis?
Bone biopsy
Lab tests WBC ESR CRP
X-ray, MRI, CT
What is the treatment of acute osteomyelitis?
Acute:
Empiric IV antibiotics
Flucloxacillin (if resistance)
vancomycin IV
Chronic:
Often require surgery
same antibiotics but duration woul be longer like 6-12 weeks
What is the monitoring for osteomyelitis?
Fever
lab
Liver
Kidney
Glucocorticoids can increase in your blood what?
WBC
What is Septic arthritis?
Infection of joint
Pathogenesis of Septic arthritis?
From blood
Trauma
Pre-existing bony infection
and bacteria enters joints and prduce inflammation to synovial membrane as a result cartilage breakdown
Risk factors for septic arthritis
gout or OA or RA
80 years of age or older
Diabetes
joint surgery
What are the symptoms of Septic arthritis?
Pain
Swelling
Tenderness
Common“Knee joints”
How to Diagnosis septic arthritis?
Synovial fluid culture
Treatment of Septic arthritis?
flucloxacillin IV but shorter period of time 2-4 weeks
if resistance Vencomycin IV
What is reactive arthritis?
develops soon after or during an infection somewhere else in the body
Most common in men 20-50 years old
