MS Flashcards
what are some MS deficits
- fatigue
- spasticity
- deconditioning
- weakness
- numbnes and decreased sensation
- decreased coordination and motor control
- impaired balance
- pain
what do symptoms depend on
lesion location
what is it
chronic
attackof CNS
autoimmune disease
who is it most common in
women > men
young adults late teeens to 35
what are common barriers to exercise
- fatigue
- pain
- heat sensitivity
which areas of the nervous system does it affect
Brain and spinal cord
what is the most common type when newly diagnosed
relapsing remitting
which cells are responsbible for myelin production in the CNS
oligodendrocytes
what are the most common initial presentation
optic neuritis, sensory changes, weakness
what is the mcdonald criteria
- MRI lesions in 2 of the 4 areas
- relapse and/or new lesions in MRI
true or false:
there are disease modifying drugs that significantly decrease new lesion formation, progression of the disease and relapse rates
true
what causes MS
- genes
- environment
- auto immunity
which cell mediated disease is MS
T cell
-overproudction of inflammatory cytokines
what does acute treatment do
- shortens attacks
- does not alter severity of neuro impairment
