Movement Disorders Flashcards
Hoehn and yahr scale stages
- Unilateral involvement only usually with minimal or no functional disability
- bilateral or midline involvement without impairment of balance
- Bilateral disease : mild to moderate disability with impaired postural reflexes ; physically independent.
- Severely disabling disease ; still able to walk or stand unassisted
- Confinement to bed or wheelchair unless aided
Hoehn and Yahr scale severity
Stage 1 and 2 are mild
Stage 3 moderate
Stage 4+5 severe
Goals of Parkinson’s disease therapy
Effective control of symptoms
Motor fluctuation control
Continuous control of ought the day and night
Maintainance of independence and quality of life
Motor problems in PD
Balance, walking + freezing
Signs in patient writing with PD
Small writing /
Tremors when writing indicate
Not necessary Parkinson’s
PD most common motor problems
Urination Libido Insomnia Concentration Anxiety Restless legs
Progression of Pd
Unilateral-> bilateral -> motor complications-> instability and falls-> psychosisx> dementia
Aspect imaging shows what
Full stop comma looking dopamine cells (assymetric)
Treatments main aim is
Dopamine replacement
Which type of dopamine replacement
Levedopa- tablet
Or dopamine agonist
Levedopa side effect
Can overdose and cause dyskinesia) too much movement
How much levedopa should you take
As disease progresses, overdose occurs at lower levels