Crytstal Arthritis

Question 1

Uris acid is a product of

Answer 1

Purine metabolism

Question 2

Hyperuricaemia

Answer 2

Males > 0.42 mmol/L

Females >0.36mmol/L

Question 3

Risk factor of gout

Answer 3

Huperuricaemia
Alcohol persistent consumption
High BMI
Old age
Male

Question 4

Clinical features

Answer 4

Severe pain/rapid onset

Always in singular joint first

Question 5

Technique to diagnose

Answer 5

Arthrocentisis

Question 6

Diagnosis of gout and pseudogout

Answer 6

Gout: negative biophringent crystal

Psuedogout: positive biophringent Crystal (ureic acid crystals)

Question 7

Prevention strategies

Answer 7

Dietary restriction exogenous purines

Reduce drugs that reduce renal clearance

Stop taking drugs with endogenous purines

Question 8

Acute setting strategy

Answer 8

NSAID (naproxen) 500mg 5 days

Question 9

When would your acute treatment change

Answer 9

If patient is suffering with kidney disease we give presdinolone instead of NSAIDs (naproxen)

Question 10

Drug to prevent reoccurrence

Answer 10

Xonthine oxidase inhibitors

Question 11

Pseudogout other name

Answer 11

Calcium pryophosphate disease

Question 12

What happens in pseudogout

Answer 12

Lose cartillage and develop calcium crystals

Question 13

Risk factors

Answer 13

Age
Prior joint trauma
Haemochromotosis

Question 14

Urges of pseudogout

Answer 14

Rapid onset 
Peaks in 24 hours 
Fever 
Erythema 
Resolution in 3-4 days

Question 15

Pseudogout crystals

Answer 15

Small ramboid shape positive biophringent crystal

Question 16

Acute and long term treatment for pseudogout

Answer 16

Acute same as gout

Long term no treatment just therapy