Inflammation In Ageing

Question 1

Telomere

Answer 1

Shortening

Question 2

Pro ageing

Answer 2

IL 6
CRP
HSP90
TNF alpha

Question 3

Anti ageing

Answer 3

TGF-bets
IL10
cortis9l

Question 4

Presentation of of inflammation change how in older age ?

Answer 4

Atypical
Lack fever
Non specific symptoms

Question 5

Tuberculosis reactivation

Answer 5

Latent disease

Later in life disease may be reactive due to immune suppression, illness or aging

Question 6

Herpes virus zoster (HHV3) is

Answer 6

Shingles and a reactivTion of chicken pox

Not due to antibody

Question 7

T cell repertoire in elderly

Answer 7

Absolute T cell count falls

Peripheral regulatory T cell pool increases

Question 8

Herpes viruse : CMV (HHV5)

Answer 8

Present in 60-90% adults

Asymptomatic in immunocompetent host

Question 9

CMV positively associated with immunosenescence

Answer 9

Gradual determination of immune system due to age

Question 10

Autoantibodies in ageing

Answer 10

More autoantibodies but lower incidence of autoimmune diseases

Question 11

Autoimmune diseases are rare as

Answer 11

Naive T cells dismiss in elderly

Question 12

IL6 needed for

Answer 12

CRP creation which causes premature aging

Question 13

Risk of cancer increase with ages?

Answer 13

Yes

But over 80 risk of Brest cancer goes down in women