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Neurology > Movement Disorders > Flashcards

Movement Disorders Flashcards

1
Q

modulate motor cortical activity but also the activity of the association cortex, in the frontal lobes

A

basal ganglia

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2
Q

refers to the basal ganglia

A

Extrapyramidal

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3
Q

locations in brain where movement disorders originate

A

extrapyramidal or cerebellar dysfunction

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4
Q

chorea

A

dance-like movts

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5
Q

sx include Chronic progressive chorea Psychological changes, Dementia, myoclonus, nystagmus, dystonia

A

Huntington’s

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6
Q

Decrease of GABA and GABA receptors in the basal ganglia. Decrease in Ach

A

Huntington’s pathophysiology

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7
Q

Tx to suppress chorea

A

Tetrabenazine (VAMT Inhibitor)

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8
Q

Most common cause of tremor

A

essential tremor

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9
Q

Tremor that is More prominent with action than rest. Frequency of tremor is constant

A

essential tremor

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10
Q

Palliates essential tremor

A

ETOH

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11
Q

Pharmological tx for essential tremor

A

Propranolol (Inderol), Atenolol (Tenormin). Mysoline (Primidone) or Gabapentin (Neurontin) -anticonvulsants

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12
Q

Characterized by Resting and postural Tremor, Rigidity, Akinesia (Bradykinesia), Postural instability

A

Parkinson’s

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13
Q

Leading cause of neurologic disease in patients over age 65

A

Parkinson’s

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14
Q

Marked loss of dopaminergic nerve terminals in the substantia nigra. increase in cholinergic interneuron activity

A

Pathophysiology of Parkinson’s

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15
Q

Most visible manifestation of Parkinson’s

A

tremor (often pill-rolling). Appears at rest. Disappears with movement and sleep

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16
Q

Most debilitating symptom of Parkinson’s

A

Akinesia (Bradykinesia). Feel frozen in place, can’t stop suddenly (high risk of falls), or turn

17
Q

gold standard for diagnosing Parkinson’s

A

neurological exam

18
Q

What bulking agent should you not give to Parkinson’s patient’s for constipation?

A

REGLAN dopamine receptor antagonist

19
Q

Uses electric pulse generators to control symptoms attached to STN or thalamus

A

Deep Brain Stimulation

20
Q

Ethnic factors for RLS

A

more common in North American, Europeans

21
Q

Pharm tx that may help RLS only after other causes have been ruled out

A

parkinson’s meds, Lyrica, opiods, gabapentin

Neurology (16 decks)

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