Mouth lesions Flashcards

1
Q

Gingivitis

A

red, swollen, bleeding gingiva, reversible if treated

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2
Q

Periodontal disease

A

bone loss, periodontal pocket formation, tooth mobility may be present, halitosis (bad breath)

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3
Q

Herpes simplex virus

general

A
(can cross the waist)
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4
Q

HSV-1

general

A
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5
Q

reccurant oral herpes labialis

Cold sore (describe them)

A
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6
Q

Reccurant intraoral herpes

general

A
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7
Q
A

recurrent intraoral herpes

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8
Q

Acute primary herpetic gingivostomatitis

general, Sx, Tx

A
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9
Q
A
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10
Q
A

acute herpetic gingivostomatitis

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11
Q

acute herpetic gingivostomatitis

Tx

A

Tx for more generalized oral lesions of primary infection is mostly palliative, using soothing mouth rinses and analgesics

Magic mouthwash:
Viscous lidocaine
Benadryl
Mylanta
Nystatin
Prednisone

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12
Q

acute herpetic gingivostomatitis

Treatment (non-palliative)

A

Oral antivirals:
Acyclovir
Valacyclovir
Famcyclovir

Topical antivirals:
Acyclovir
Penciclovir

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13
Q

Necrotizing Ulcerative Gingivitis

general
Offending pathogens

A

Infection with spirochetes AND fusiform bacilli
Common in young adults under stress (sound familiar?!); also seen in poor oral hygiene, patients with HIV/ immunocompromised
Smoking increases risk
Painful gingival inflammation and tissue death (necrosis)
Bleeding, halitosis, fever, cervical lymphadenopathy

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14
Q

Necrotizing Ulcerative Gingivitis

Dx and Tx 4

A

Diagnosis is usually clinical; usually refer out for full diagnosis and treatment (periodontal specialist if possible)

Tx: warm chlorhexidine or diluted peroxide rinses PLUS antibiotics (metronidazole and PCN); will need to debride dead tissue if severe

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15
Q

Oral candidiasis

General

A

opportunistic fungal infection
most common form in Candida albicans
mostly in immunocompromised ots, elderly and infants
30-50% of humans have C. albicans

also called Thrush, angular chilitis, median rhomboid glossitis, denture sore mouth, yeast infection.

can be acute, chronic, or mucocutaneous

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16
Q

Candidiasis

Predisposing factors

A
17
Q

Candidiasis

classifications

A
18
Q

candidiasis

S/Sx

A

Small soft plaques
wiping away the plaques leaves a painful erythametous, eroded, or ulcerated surface.
if the plaques have not been disturbed, the associated sx are minimal.

found in buccal mucosa, mucobuccal folds, the oropharynx, and lateral aspects of the tongue.

Severe cases: pts may complain of tenderness, burning, and dysphagia.

19
Q

Acute erythametous candidiasis

general

A

generalized red lesion
caused by ABx Tx
Painful

ABx withdrawal will improve Sx

20
Q

Chronic erythametous candidiasis

(Denture stomatitis)

A
21
Q

Chronic erythametous candidiasis/ Denture stomatitis

Tx

A

remove dentures at night
clean dentures with strong antiseptic solution
good oral hygiene
peridex mouthwash

22
Q

Aphthous Stomatitis

causes

A
23
Q

Apthous Ulcers

Types

A
24
Q

Minor apthous ulcer

general

A
25
Q

Minor apthous ulcer

Tx Meds and diet(4)

A

topical steroid gel is most successful
systemic steroid for 1 week
oral rinse: Chlorohexidine

dietary changes: folic acid, B12, iron, remove gluten

reduction of oral lesion coincides with improvements in GI tract

26
Q

Leukoplakia

General

A
27
Q

leukoplakia

general

appearance, location, causes

A
28
Q

leukoplakia

Dx and Tx

A
29
Q

Hairy leukoplakia

general and Tx

A

Lateral border of tongue
Common early finding in HIV but can also occur in organ transplant patients, EBV, long term corticosteroid use
Like regular leukoplakia BUT a little thicker and appears hairy
Treat with antivirals (acyclovir, famciclovir, valacyclovir) but only get temporary relief

30
Q

Erythroplakia

general

A

Similar to leukoplakia but it is erythematous in appearance
90% are dysplasia or carcinoma (“precancer” or cancer)
DDx is basically anything that causes a change to the tongue (such as candidiasis, oral lichen planus, glossitis, etc)

Biopsy

31
Q

Oral Lichen Planus

general and dx

A

“lacy” leukoplakia
Erosive
Chronic inflammatory autoimmune disease
Must biopsy to diagnose and to be sure it isn’t squamous cell carcinoma

32
Q

Oral Lichen Planus

Tx

A

Treatment: manage pain- no cure and can’t really shorten length of episodes
Medications: daily topical corticosteroids are 1st line, can try cyclosporine, retinoids and tacrolimus

33
Q

Squamous Cell Carcinoma

general

A
34
Q

Squamous Cell carcinoma

Tx

A

Surgical excision
radiation/chemo

successful Tx depends on the size, site, and stage of the lesion
early detection is KEY!

35
Q

Taste

Salt

A

Saltreceptors use a Na+channel to sense the [Na+] in the mouth.

36
Q

Tatse

Sour

A

Sournessreceptors respond toacidity (H+).

37
Q

Taste

Sweetness

A

Sweetnessreceptors use intracellular second messengers. (For example, binding of a sugar may stimulate formation of cyclic adenosine monophosphate (cAMP), which inhibits a K+channel and depolarizes the receptor cell membrane.)

38
Q

Taste

bitterness

A

Bitternessreceptors use more than one transduction mechanism, depending on the chemical. Mechanisms include direct binding to K+channels and changes in second messengers.

39
Q

taste

Umami

A

Umami(Japanese word meaning “delicious”) receptors respond to amino acids, particularly glutamate.