Motor System Flashcards
What is the difference between upper and lower motor neuron?
Upper - brain, supply input to LMN
Lower - soma in brainstem and ventral horn of spinal cord
Where do lower motor neurons receive input from?
- UMN
- proprioceptors
- interneurons
What are the two types of lower motor neuron?
alpha - innervate the bulk of fibres that generate force
gamma - innervate a sensory organ (muscle spindle)
State the difference between axial, proximal and distal muscles
Axial - movements of the trunk
Proximal - shoulder, elbow, pelvis
Distal - hands, feet and digits
What causes the two enlargements of the spinal cord?
Uneven distribution of motor neurons particularly distal and proximal ones
Where are the two spinal cord enlargements?
Cervical - C3-T1
Lumbar - L1-S3
What is a motor unit?
All the fibres supplied by one alpha motor neuron
What is a motor neuron pool?
A collection of alpha motor neurons that innervate a single muscle
Name two things force of contraction depends on
- frequency of AP discharge of alpha motor neuron
- recruitment of additional synergistic motor units
How are the LMN arranged?
LMN innervating axial muscles are medial to those that innervate distal muscles
Flexors are dorsal to extensors
What does activation of muscle fibres depend on?
- firing rate of LMNs
- number of LMNs active
- co-ordination of movement
How does a muscle movement arise?
Summation of twitches causes a sustained contraction as the number of APs increases
What differentiates slow and fast fibres?
Differ in how quickly myosin ATPase splits ATP to provide fro cross bridge cycling
Describe slow type 1 fibres
ATP largely derived from oxidative phosphorylation, slow contraction and relaxation means it is fatigue resistant
High myoglobin - red fibres
Low tension, small alpha motor neurons, low threshold for antigravity sustained movement
Describe type IIa fibres
ATP derived from oxidative phosphorylation, fast contraction and relaxation but fatigue resistant
Red and reasonably well vascularised
High tension, intermediate alpha motor neuron and threshold for sustained locomotion
Describe type IIb/x fibres
ATP derived from glycolysis, fast contraction and susceptible to fatigue
Pale and poorly vascularised
High tension, large alpha motor neurons and threshold for burst power
What type of fibre does not occur in mammals?
IIb
In what order are alpha motor neurons recruited?
In order of size, allows fine control of muscle force across a range of tensions
Name the parts of a muscle spindle
- fibrous capsule
- intrafusal muscle fibres
- sensory afferents (Ia fast conducting)
- gamma motor neurons
Describe the monosynaptic reflex
- Stretch of muscle spindle
- Activation of Ia afferents
- Excitatory synapse in spinal cord
- Activation of alpha motor neuron
- Contraction of homoymous muscle