more cards Flashcards
Sulfonamides - how do they inhibit bacteria
Bacteriostatic by inhibiting the synthesis of folate
Sulfonamides are active against
gram + cocci and Gram - Bacilli
Sulfonamides are used in treatmetn for
UTI
Malaria
Toxoplasmosis
Ulcerative colitis
What sulfonamide is used in ulcerative colitis
Sulfasalazine
Can you use sulfa in pregnancy
no
Sulfonamide teaching
Avoid prolonged sun exposure
wear sunscreen
Sulfonamide interaction
Stephen johnsons syndrome
Hemolytic anemia - in patients with G6PD deficiency
Explain Stephen Johnsons syndrome
Starts with peeling of skin and burning
stop drug immediately
let me know if you have the start of any kind of rash
signs of hemolytic anemia
fever
palor
jaundice
Vit C or acidifying drinks and sulfonamides
increased r/o crystalluria
need water to flush it through
need 8-10 glasses of water so if on fluid restrictions this is not a good drug
what is the age range for sulfonamides
not less than 2 mos
not pregnant after 32 weeks gestation
not breastfeeding
older patients and sulfonamides
more likely to have severe side effects
gonorrhea therapy
ceftriaxone and azithromycin dual therapy
