Mood stabilizer Flashcards
Which mood stabilizer is used as the first line of tx?
lithium
What is lithium effective in tx of?
- acute mania
- acute Bipolar depression
- Prevention of manic episodes
How long does it take for lithium to have a full response?
3-6 weeks
Are NSAIDS contraindicated with lithium?
duh
What is the therapeutic level of lithium?
0.5-1.2
what therapeutic level shows signs of early lithium toxicity?
1.2-1.5
What therapeutic level shows signs of advanced lithium toxicity?
1.5-2
What therapeutic level shows signs of severe lithium toxicity?
2+
What are COMMON EXPECTED side effects of lithium?
- fine hand tremors
- polyuria, mild thirst
- nausea
- weight gain
- sedation
- acne
Signs of early lithium toxicity
- N/V/D
- slurred speech
- Muscle weakness
signs of advanced lithium toxicity
- Coarse hand tremor
- GI upset
- Mental confusion
- Muscle hyper irritability
- EEG changes
- incoordination
what is the tx for someone experiencing advanced signs of lithium toxicity?
saline bolus
signs of severe lithium toxicity
- ataxia
- serious EEG changes
- Blurred vision
- Clonic movements, seizures
- Stupor
- Coma/Death
Long term side effects of lithium
HYPOthyroidism
Kidney dysfunction