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mental health > Antidepressants > Flashcards

Antidepressants Flashcards

1
Q

What is key with antidepressants?

A

safety safety safety

bc of increased risk of suicide within the first week of taking it

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2
Q

What are the different SSRIs

A
  1. Citalopram
  2. Escitalopram
  3. Fluoxetine
  4. Paroxetine
  5. Sertraline
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3
Q

What are SSRIs useful in tx for?

A
  1. Depression w anxiety
  2. Panic disorder
  3. PTSD
  4. OCD
  5. bulimia
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4
Q

Side effects of SSRIs

A
  1. Sleep disturbance
  2. Sexual dysfunction
  3. Reduced appetite
  4. Rash/SJS
  5. Tension headaches
  6. Hyponatremia
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5
Q

How long does it take SSRIs to take full effect?

A

2-3 weeks for full effect

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6
Q

Symptoms of serotonin syndrome

SHIVERS

A

Shivering
Hyperreflexia
Increased temp
VS instability
Encephalopathy
Restlessness
Sweating

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7
Q

Do SSRIs increase bleeding tendencies?

A

YES

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8
Q

What are the different SNRIs?

A
  1. Venlafaxine
  2. Desvenlafaxine
  3. Duloxetine
  4. Levomilnacipran
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9
Q

Do SSRIs and SNRIs have the same symptoms?

A

yes

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10
Q

What are SNRIs useful in tx for?

A
  1. MDD
  2. anxiety disorder
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11
Q

What are the adverse effects of SNRIs?

A

Serotonin syndrome
Hyponatremia

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12
Q

What is trazodone used for?

A

mainly used for sleep but its an antidepressant

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13
Q

What should be known about trazodone?

A
  1. extremely sedating
  2. CAN be given in adjunct with SSRIs
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14
Q

What is an adverse effect of Trazodone?

A

Priapism

aka painful erect penisssss

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15
Q

What are the different TCAs?

A
  1. Amitriptyline
  2. Doxepin
  3. Imipramine
  4. Nortriptyline
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16
Q

What stimulating effects do TCAs target?

A

Target fatigue and lethargy

17
Q

What sedating effects do TCAs target?

A

target agitation or restlessness

18
Q

What are the anticholinergic side effects of TCAs?

A
  1. Dry Mouth
  2. Blurred vision
  3. Tachycardia
  4. Constipation
  5. Urinary retention
  6. Esophageal reflux
  7. Photophobia
  8. Sexual dysfunction
19
Q

What two anticholinergic effects of TCAs are considered a medical emergency?

A

constipation and urinary retention

20
Q

How long odes it take for TCAs to reach full effect?

A

4-8 weeks

21
Q

What are the adverse effects of TCAs?

A
  1. orthostatic hypotension
  2. Dysrythmias
  3. MI
  4. Heart block
22
Q

Which medication class is very cardio toxic?

A

TCAs

23
Q

What are the contraindications of TCAs?

A
  1. Recent MI
  2. Narrow angle glaucoma
  3. Benign prostatic
  4. Hypertrophy
  5. seizures
  6. preggo
24
Q

What are the different MAOIs?

A
  1. Phenelzine
  2. Tranylcypromine
  3. Isocarboxazid
  4. Selegiline
25
Q

What can MAOIs cause?

A

HTN crisis

26
Q

What are the symptoms of a HTN crisis?

A
  1. Severe HA or blurry vision
  2. chest pian
  3. tachycardia
  4. SOB
  5. Diaphoresis
  6. Anxiety
  7. Mental status change
  8. confusion
    N/V
27
Q

If switching from SSRI to MAOI how long is the wash out period?

A

5 week cleanse

28
Q

if switching from MAOI to SSRI how long is the cleanse?

A

14 days

29
Q

What foods do you avoid when taking MAOIs?

A

tyramine foods need to be avoided

Will cause HTN if eaten

30
Q

What are the contraindications of MAOIs?

A
  1. CVD
  2. HTN
  3. CHF
  4. liver disease
  5. recurrent ot severe HA
  6. Recent surgery
31
Q

Which antidepressant is mainly used for smoking cessation and prevention of seasonal depression?

A

Buproprion

32
Q

What are the adverse effects of bupropion?

A
  1. Appetite suppression
  2. seizures
33
Q

What medication targets suicide ideation?

A

Ketamine

34
Q

How can Ketamine be administered?

A

IV and nasal

35
Q

What are the side effects of ketamine?

A

increased BP, HR
Disassociation

36
Q

alternative treatments for depression

A

light therapy
st johns wort

mental health (14 decks)

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