Mood Disorders Flashcards
description of one’s internal emotional state
Mood
distinct period of time in which some abnormal mood is present
mood episode
defined by their patters of mood episodes
mood disorders
DSM-IV criteria to dx Major Depressive Episode?
Must have five of the following sx for at least a 2 week period:
1. depressed mood 2. Anhedonia 3. change in appetite or body weight 4. feelings of worthlessness or guilt 5. Insomnia or hypersomnia 6. diminished concentration 7. psychomotor agitation or retardation ( restlessness or slowness) 8. fatigue or loss of energy 9. recurrent thoughts of death or suicide
SIG E. CAPS (Sleep, Interest, Guilt, Energy, Concentration, Appetite, Psychomotor activity, Suicidal ideation )
criteria for a manic episode?
at least 3 of the following lasting at least 1 week:
Distractability, inflated self esteem or grandiosity, increase in goal directed activity, decreased need for sleep, flight of ideas or race of thoughts, more talkative or pressured speech, excessive involvement in pleasurable activities that have a high risk of negative consequences
DIG FAST (Distractibility, Insomnia/impulsive behavior, Grandiosity, Flight of ideas, Activity, speech (pressured)
Thoughtlessness)
Mania vs. Hypomania: Duration? Social or occupational functioning? Hospitatlization? Psychotic features?
Mania- at least 7 days, hypomania at least 4 days
Mania- severe impairment in social or occupational functioning, hypomania- no marked impairment
Mania- requires hospitalization, hypo does not
Mania may have psychotic features, hypomania does not
? patients are at very high risk for developing depression
Stroke patients
has the highest rate of suicide of any disorder
major depressive disorder
Sleep problems assoicated with MDD
multiple awakenings, initial and terminal insomnia (hard to fall asleep or waking up early), hypersomnia, REM sleep shifted to earlier in night and stage 3 and 4 decreased
Main neurotransmitter change found in depressed patients
Decreased brain and CSF levels of serotonin and its main metabolite 5-HIAA
Hormonal changes seen in deprssion
High Cortisol
Abnormal thyroid axis
Cancer that has the highest association with depression
Pancreatic Cancer
Time it takes for antidepressants to work?
4-8 weeks
marked by autonomic instability, hyperthermia, and seizures. Coma or death may result
Serotonin Syndrome
Patients that may not be able to tolerate the side effects of antidepressants?
Elderly and pregnant women
a type of depression that usually resolves without medication
postpartum depression