MONOAMINE OXIDASE INHIBITORS (MAOIs)

Question 1

It inhibits monoamine oxidase

Answer 1

Monoamine oxidase inhibitors (MAOIs)

Question 2

MAOIs are reserved for px who have not responded to ________, because of their low safety margin.

Answer 2

TCAs or SSRIs

Question 3

It limits the breakdown of ________ in the CNS neurons.

Answer 3

NE, dopamine and serotonin

Question 4

first drugs approved to treat depression in 1950.

Answer 4

MAOIs

Question 5

What are the example drugs of MAOIs

Answer 5

Isocarboxazid (Marplan)
Phenelzine (Nardil)
Tranylcypromine (Parnate)

Question 6

What are the most common side effects of MAOIs

Answer 6

Orthostatic hypotension, headache, insomnia, and diarrhea

Question 7

Respiratory collapse, circulatory collapse
Hypertensive crisis

Answer 7

MAOIs Serious Adverse Effects

Question 8

MAOls is used concurrently with other antidepressants or sympathomimetic drugs; vasoconstrictors or cold medication containing ________ can cause hypertensive crisis

Answer 8

phenylephrine

Question 9

Combining an MAOIs with an SRIs can produce _______

Answer 9

serotonin syndrome

Question 10

If MAO is are given with antihypertensives, the clients can experience ______

Answer 10

excessive hypotension

Question 11

______ is known to occur in clients taking MAOls with meperidine (Demerol),
Dextromethorphan pedia cares) and TCAS

Answer 11

Hyperpyrexia

Question 12

MAOls and food containing tyramine can cause ________ like avocados, bananas, raisins, papaya products, including meat tenderizers, canned figs, dairy products like, cheese (cottage cheese is okay), sour cream, yogurt, alcohol like beer, wines (especially red wines), meats like beef or chicken liver, pate, meat extracts, pickled or kippered herring pepperoni, salami, sausage, bologna/hot dogs, vegetables like pods of broad beans (fava beans), soy sauce, all yeast or yeast extracts, chocolate

Answer 12

Hypertensive Crisis

Question 13

MAOIs A client taking an MAOIs must refrain from foods that contain ________

Answer 13

tyramine

Question 14

_______ is contraindicated in cardiovascular disease, heart failure, hepatic or renal dysfunction and paranoid schizophrenia

Answer 14

Phenelzine (Nardil)

Question 15

Obtain a CBC, because MAOIs can inhibit _____

Answer 15

platelet function

Question 16

Use MAOls with caution in ________ because they may lower the seizure threshold

Answer 16

epilepsy

Question 17

There must be at least ___ days interval between the use of MAOis and other drugs

Answer 17

14 days

Question 18

Some clients may not achieve the full therapeutic benefits of an MAOIs for_____ weeks.

Answer 18

4 to 8

Question 19

Wear a _____ identifying the MAOls medication

Answer 19

medical alert bracelet

Question 20

Do you need to observe for and report signs of impending stroke or myocardial infarction (MI)

Answer 20

Yes