DRUGS FOR NEUROMUSCULAR DISORDERS

Question 1

What are the neuromuscular disorders?

Answer 1

Myasthenia Gravis
Multiple sclerosis
Muscle Spasm

Question 2

Results from lack of acetylcholine receptor sites

Answer 2

Myasthenia gravis

Question 3

Inhibit the action of the enzyme

Answer 3

ACETYLCHOLINESTERASE INHIBITORS/CHOLINESTERASE INHIBITORS

Question 4

More acetylcholine is available causing _____

Answer 4

muscle contraction

Question 5

Short half-life (given every 2 to 4 hours)

Answer 5

Neostigmine

Question 6

Intermediate half life (given every 3 to 6 hours)

Answer 6

Pyridostigmine

Question 7

Result from overdosing
Severe headache
Paralysis arrest

Answer 7

Cholinergic Crisis

Question 8

Antidote for cholinergic crisis

Answer 8

Atropine sulfate

Question 9

What is tensilon test?

Answer 9

If muscle weakness become more severe- overdosing (cholinergic crisis)
If muscle weakness improve- underdosing( myasthenic crisis)

Question 10

Autoimmune disease
Attacks myelin sheath of nerve fibers
Weakness and spasticity

Answer 10

Multiple Sclerosis

Question 11

Treatment for multiple sclerosis

Answer 11

Glucocorticoids
Biologic Response Modifiers
Immunosuppressants