Monitoring Drug Therapy 2 Flashcards
Where is creatine produced
produced continuously as a byproduct of normal muscle metabolism and is eliminated by the kidneys
what does plasma concentration depend on
muscle mass
breakdown
ability of the kidney
what indicates an estimation of renal function
creatinine levels
what are three types of renal disease
pre renal
renal
post renal
what is pre renal disease
reduced blod flow to the kidneys
what is renal disease
intrinsice damage to the kidney itself
what is post renal disease
downstream issue usually causing UTI
what is gfr
glomerular filtrate rate
what is the best way to measure kidney function
GFR
what does GFR involve
injecting a contrast dye into the kidney and monitoring the rate of travel throug hthe kidney which is not possible in the majority of patients
what does eGFR use
MDRD equation
which takes sex age weight and ethnicity into account
what are the 5 stages of renal disease
GFR >90 normal function
GFR >60-89 midly reduced function
GFR> 30-59 moderately reduced function
GFR> 15- 29 severely reduced function
GFR> 15 or on dialysis
What is an AKi
Acute kidney injury
what is a CKD
chronic kidney disease
How do we calculate renal function
)urine conc x urine flow rate) / serum creatinine conc
