ADR Flashcards
What is an ADR
unwanted or harmful reaction experienced following the administration of a drug or a combination and is suspected to be related to the drug
what are the two types of ADR
type a
type b
what is the pharmacists role in managing pharmacists ADRs
identify patients at risk of ADRs
identify drugs known to produce ADR and monitor patient appropriately
avoid use of drugs causing ADrs where an equally effective and safer alternative exists
review patients medicines
ensure patient are counselled on the correct use of their medicines and possible side effects
reporting ADRs
Who is at risk of an ADR
extremes of age female polypharmacy incurrent diseases a history of intolerance or hypersensitivity
what are some common drugs that can cause ADRs
NSAIDS DIURETICS WARFARIN ACE INHIBITORS ANTIDEPRRESSANTS + LITHIUM
what are NSAIDS associated with (body)
gastrointestinal toxicity
what are the 3 highest risk NSAIDS
piroixcam ketoprofen ketoralac
how do we minimise GI damage from NSAIDS
switch to another analgesiac
use nsaids associated with low risk
do not use morethan one at a time
identify patients at risk
prophylaxis with proton pump inhibitor
What ADRs should loop and thiazide diuretics
hypovolemia
hypokalaemia
hyponatremia
hyperuricemia
when should a k sparing diuretic be used
hyperkalaemia
what are some ADRs caused by warfarin
GI bleeding
haematuria
High INR
haematoma
What are some ADRs caused by Ace inhibitors
cough angioedema increase K+ Acute renal failure hypotension
what are some Opiates ADRs
constipation vomiting confusion urinary retention respiratory depression
When prescribing what should the healthcare practitioner
Check any recent opiods
Dose
Formulation
Frequency of administration
Any other analgeic medicines prescribed for the patient
What are some ADRs caused by digoxin toxicity
nausea
visual distrubances
arrhythmias
