Money Viral

Question 1

DOC for chemoprophylaxis in areas with chloroquine resistant P. falciparum

Answer 1

• • Doxycycline (Vibramycin)

Question 2

Shingles (Herpes Zoster): Antiviral Therapy

Answer 2

• -Valacyclovir
• -Famciclovir
• -Acyclovir (5 x per day for 7 days)

Question 3

DOC for Lymphatic Filariasis

Answer 3

• • Diethylcarbamazine (DEC)

Question 4

DOC for Pneumpcystis jiroveci pneumonia (PCP)

Answer 4

–Sulfamethoxazole-Trimethoprim (Septra)

Question 5

The only FDA approved drug for treatment-experienced patients .
Drug MOA: blocks HIV fusion with the CD4 cell and block entry into the human cell

Answer 5

• • Enfuvirtide

[Fusion Inhibitors]

Question 6

Approved drug regiment for HIV Pre-Exposure Prophylaxis (PrEP)

Answer 6

• • Emtricitabine (FTC) Daily
• PLUS-
• –Tenofovir disoproxil fumarate (TDF) (Truvada)

Question 7

DOC to prevent CMV infection after transplant

Answer 7

• • Valganciclovir (Valcyte) PO

Question 8

1st line DRUGS for the treatment and prevention of Cytomegalovirus (CMV) infections

Answer 8

Ganciclovir (Cytovene-IV)

- Valganciclovir PO (prodrug)

Question 9

DOC for Management of all HIV(+) pregnant women

ANTEPARTUM stage

Answer 9

• -Emtricitabine/Tenofovir (Truvada) daily

- -Raltegravir (Isentress) twice a day

Question 10

HBeAg Positive

Answer 10

1 st Line(4-12 mos):
--IFNa
--PEG-IFNa
2 nd Line (>12 mos)
--Entecavir or Tenofovir PO

Question 11

DOC for Tx HBV

Answer 11

Pegasys

• -a= Preferred for HBV
• -b= FDA approved for HBV

Question 12

HBeAg Negative:

Answer 12

1 st Line(at least 12 mos):
--IFNa
--PEG-IFNa
2 nd Line (>12 mos)
--Entecavir or Tenofovir PO

Question 13

DOC for Tx Influenza Virus in Pregnant Women

Answer 13

Oseltamivir

Question 14

Occupational (within 72 hrs) Post-Exposure Prophylaxis (PEP) use for 28 days & nPEP

Answer 14

• -Emtricitabine/Tenofovir (Truvada) daily

- -Raltegravir (Isentress) twice a day

Question 15

DOC in sensitive P. falciparum

Answer 15

• • Chloroquine (Aralen)

Question 16

Tx of choice of hydrocele due to Lymphatic Filariasis (e.g roundworm, elephantiasis)

Answer 16

• • Surgery is treatment of choice for hydrocele

Question 17

2nd line DRUGS for the treatment and prevention of Cytomegalovirus (CMV) infections

Answer 17

• Foscarnet (Foscavir) IV

- Cidofovir (Vistide) IV

Question 18

DOC for Trichonomas vaginalis

Answer 18

–Metronidazole or Tindazole

Question 19

DOC Herpes Encephalitis

Answer 19

• • Acyclovir IV 5-10mg/kg every 8 hours for 2-7 days,

Followed by ORAL antiviral therapy for at least 10 days

Question 20

DOC Genital Herpes Simplex

Answer 20

–Valacyclovir

Question 21

Preferred treatment options for Development of Resistant HBV

Answer 21

Lamivudine or Telbivudine resistance :
---Add Adefovir or Tenofovir or
---Change to Entecavir
Adefovir resistance :
----Add Lamivudine
Entecavir resistance :
---Change to Tenofovir

Question 22

Entecavir and tenofovir are preferred oral agents for what type patient populations

Answer 22

• -HBeAg positive

- -HBeAg negative

Question 23

DOC for severe or difficult-to-treat HSV infections

Answer 23

• • Acyclovir IV

Question 24

DOC for initial mild to moderate episodes of C-diff

Answer 24

–Metronidazole

Question 25

DOC for Management of all HIV(+) pregnant women

INTRAPARTUM stage

Answer 25

–add IV Zidovudine

reduces rate of mother-to-newborn transmission

Question 26

HIV infant prophylaxis

Answer 26

• -low risk: Zidovudine 4-6 wk

- -high risk: combo regimen