Money Flashcards
DOC Brucellosis
- Doxycycline
Cephalosporin -Not for neonates: Ca2+ crystals in lungs and biliary slugging
- Ceftriaxone
Aminoglycosides are effective against what organisms?
—Effective against E.Coli, Klebsiella, P. Areuginosa**, Acinobacter (gram –ve)
DOC ACTIVE TB disease in Pregnant Women
–INH, Rifampin, and Ethambutol for 9 mos
don’t use Streptomycin
DOC in invasive pulmonary or extra pulmonary infections caused by Candida Spp.
- Voriconazole (Vfend)
DOC Plague [Yersinia pestis] (gram Neg Coccobacillus)
Streptomycin IV or Gentamicin
—-Alternatives : Doxycycline or ciprofloxacin
DOC to treat N. gonorrhea infections of the cervix, urethra, and rectum
- Ceftriaxone (Rocephin) IV
First line agent for animal bites
- Amoxicillin/Clavulanate (Augmentin) PO
Drug of choice to treat ANTHRAX (Inhalation, Cutaneous and GI)
- Ciprofloxacin or Doxycycline
DOC for tx TB Infection 4 mos
- Rifampin
Preferred for SEVERE Clostridium Difficile [C. Difficile] infection
- Vancomycin PO x 10-14d
DOC for Tx for PCN sensitive Gangrene [C. perfringen]
- Natural Penicillins -1st Generation
DOC for Onychomycosis
- Terbinafine (Lamisil) or Itraconazole PO; toenails 12 wk, fingernail 6 wk
DOCs used in Tx Active TB Treatment in Pregnancy
- Isoniazid [INH], Rifampin, and Ethambutol for 9 months
DOC for Mycobacterium Avium Complex (MAC)
- Rifabutin
Multidrug Resistant Organisms (MDRO)
- Methicillin resistant Staphylococcus aureus (MRSA)
- Vancomycin resistant Enterococci (VRE)
- Extended Spectrum beta-lactamase (ESBL)
- Klebsiella pneumoniae carbapenemase (KPC)
Preferred for MILD - MODERATE Clostridium Difficile [C. Difficile] infection
- Metronidazole x 10-14d
DOC for treatment of UTI in PREGNANCY
May use x 7 days :
- -Amoxicillin
- -Nitrofurantoin [up to 37th week]
- -Cephalexin
DOC/TX Uncomplicated CYSTITIS
- -Triemethoprim (TMP)/SMX x 3 days;
- -Nitrofurantoin x 5 days OR
- -Fosfomycin x 1 dose
Cephalosporins Crosses BBB
-Ceftriaxone, cefotaxime, and ceftazidime
DOC Tularemia [Francisella tularensis]
- DOC : Streptomycin IV or Gentamicin
- —Alternatives : Doxycycline or ciprofloxacin
DOC for Impetigo
- Mupirocin (Bactroban)-because of MRSA coverage
DOC for preferred 3 months therapy of LTBI in ONLY person 12 years or older
DOC for preferred 3 months therapy of LTBI in ONLY person 12 years or older
- - Isoniazid and Rifapentine
TX M. leprae [aka Hansen’s disease]
Dapsone + Rifampin x 6-12 mo
add Cofazimine if severe and take regimen 12-24 mo
DOC in treatment of the combination for M. tuberculosis, M. leprae and M. kansasii antigens
- Rifampin
DOC Fungal Pneumonia that does not respond to antifungals
- Sulfamethoxazole-Trimethoprim (Septra)
DOC for the treatment of latent TB
- Isoniazid (INH)
[Must add pyridoxine (B6) to prevent drug-induced central and peripheral neuropathy ]
DOC [therapy of choice] preferred for W/o contraindications LTBI in Children 2-11; Adults, HIV Pt &
Pregnant Women
- 9 months: Isoniazid PLUS Pyridoxine/vitamin B6 supplements
Human bites DOC
- Early : Amoxicillin-Clavulanate PO 5D (1st line cat/dog bites)
- Later : Ampicillin/Sulbactam IV Q6H or Cefoxitin 2 grams IV q 8h.
- PCN allergic : Clindamycin + either Ciprofloxacin or TMP/SMX
DOC used in Prophylaxis against invasive fungal infections in immunocompromised patients
- Fluconazole (Diflucan)
DOC for serious forms of invasive fungal infections
- Amphotericin B (can be used empirically & prohylactically)
DOC for first line treatment (oral) of Onychomycosis (Nail Fungus)
- Terbinafine or Itraconazole
DOC for Trichomonas vaginalis
- Metronidazole or Tindazole
DOC for Tx for Syphilis [T. pallidum]
- Penicillin G Bicillin LA
DOC Uncomplicated Vulvovaginal Candidiasis (VVC)
- Fluconazole 150mg po x 1 [ Ora l Azoles]
ALTERNATIVE : Itraconazole: 200mg po BID x 1 day
DOC Q-Fever [Coxiella burnetii]
- Doxycycline
Second line multiple drug therapy used for treatment of M. Tuberculosis [TB]
- Rifabutin
- Rifapentine &
- Streptomycin (SM)
DOC Tinea Versicolor
- Ketoconazole 2% cream apply once a day for 2 weeks
DRUGS CONTRAINDICATED for treatment of UTI in PREGNANCY
- -Fluoroquinolones
- -TMP/SMX
- -Aminoglycosides
- -Tetracyclines
Ideal choice for treatment of mild-moderate community-acquired-pneumonia [CAP]
MACROLIDES : & ketolides
- –Azithromycin
- –Erythromycin
- –Clarithromycin
DOC to eradication of nasal colonization of MRSA
- Mupirocin (Bactroban)
DOC/TX Uncomplicated PYELONEPHRITIS
- -TMP/SMX x 14 days OR
- -Fluoroquinolone x 5-7days
DOC for many susceptible fungal infections, including invasive and noninvasive candidiasis and
cryptococcal disease &
- Fluconazole (Diflucan)
DOC 1st line option for invasive candidiasis including candidemia
- Caspofungin (Cancidas)
DOC Candida infections in immunocompromised patients
- Fluconazole
- Posaconazole
- -Anidulafungin (Eraxis) - Refractory cases
- -Caspofungin (Cancidas) - Refractory cases
DOC vaginal candidiasis
- Fluconazole
DOC in Aspergillus infections
- Voriconazole (Vfend)
Resistant Vulvovaginal Candidiasis (VVC)
–Boric acid 600mg inttra-vaginal capsule x 14d
DOC/TX Community Acquired Pneumonia (CAP) with NO comorbidities
– Macrolides : Clarithromycin or Azithromycin
or
–Doxycycline
DOC used in Prophylaxis against of Asperigullos and Candida infections in immunocompromised
patients
–Posaconazole
Drug of choice for pre/post surgery not involving the abdomen
Cefazolin (Ancef)- used as surgical prophylaxis
First line multiple drug therapy used for treatment of M. Tuberculosis [TB]
- Isoniazid (INH)
- Rifampin (RIF)
- Pyrazinamide (PZA) &
- Ethambutol (EMB)
DOC 1st line option for Candida prophylaxis in hematopoietic cell transplant recipients
- Micafungin (Mycamine)
DOC 1st line option for invasive candidiasis
LTBI treatment of choice in pregnancy
- Isoniazid [INH] once daily or twice weekly for 9 months with Pyridoxine supplementation
DOC used for Prophylactically or treatment of meningitis caused meningococci or H. influenza
- Rifampin
Cephalosporins drug of choice for meningitis
- Ceftriaxone