Mondays quiz

Question 1

Adenosine - Classification

Answer 1

Endogenous nucleotide

Question 2

Adenosine - Indications (2)

Answer 2

Narrow or wide complex tachycardia with heart rate >150bpm

Question 3

Adenosine - Pregnancy Category

Answer 3

C

Question 4

Adenosine - Contraindications (7)

Answer 4

Second or third degree AV blocks, SSS, atrial flutter, atrial fibrillation, ventricular tachycardia, hypersensitivity to adenosine

Question 5

Adenosine - MoA

Answer 5

Directly acts on sinus pacemaker cells and vagal nerve terminals to decrease chronotropic and dromotropic activity without causing negative inotropic effects.

Question 6

Adenosine - Pharmacokinetics

Answer 6

Onset- 5-20sec, Peak- 20-30sec,

Question 7

Adenosine - Reactions (11)

Answer 7

Facial flushing, paresthesia, headache, diaphoresis, hypotension, chest pain, palpitations, SOB, nausea, lightheadedness, transient asystole (average 6 sec)

Question 8

Adenosine - Dosage

Answer 8

Adult: 6 mg rapid IVP. If no effect after 1-2 mins, 12 mg rapid IVP. (*12 mg may be repeated in unaffected for a max dose of 30 mg)
Peds: 0.1 - 0.2 mg/kg rapid IVP; max single dose of 12 mg

Question 9

Atropine Sulfate - Classification

Answer 9

Anticholinergic (inhibits parasympathetic)

Question 10

Atropine Sulfate - Pregnancy Category

Answer 10

C

Question 11

Atropine Sulfate - Indications (1)

Answer 11

Symptomatic Bradycardia

Question 12

Atropine Sulfate - Contraindications (4)

Answer 12

Tachycardia, hypersensitivity, unstable cardiovascular status in acute hemorrhage and myocardial ischemia

Question 13

Atropine Sulfate - MoA

Answer 13

Inhibits the actions of acetylcholine at post-ganglionic parasympathetic neuroeffector sites. These blocked vagal effects result in positive chronotropy and dromotropy without increased inotropy. Used to treat primarily bradycardias and organophosphate poisonings

Question 14

Atropine Sulfate - Pharmacokinetics

Answer 14

Onset- 1-2mins, Peak- 5min, Duration- 30-45mins

Question 15

Atropine Sulfate - Reactions (7)

Answer 15

Tachycardia, paradoxical bradycardia when pushed slowly or less than 0.5 mg, dysrhythmias, palpitations, anticholinergic effects, dizziness, headache

Question 16

Atropine Sulfate - Dosage

Answer 16

Adult: Brady: 0.5mg IVP q 3-5 mins; max dose of 3.0mg or 0.04mg/kg
Peds: 0.02 mg/kg IVP minimum dose of 0.1 mg. Max dose of 0.5mg for child and 1.0mg for a adolescent

Question 17

Amiodarone Hydrochloride - Classification

Answer 17

Class III anti-dysrhythmic (potassium channel blocker)

Question 18

Amiodarone Hydrochloride - Pregnancy Category

Answer 18

D

Question 19

Amiodarone Hydrochloride - Indications (5)

Answer 19

Stable wide complex tachycardia; V-fib; Pulseless; V-tach; *May be ordered in Junctional and Multifocal Atrial Tachycardia

Question 20

Amiodarone Hydrochloride - Contraindications (5)

Answer 20

Breast-feeding patients in cardiogenic shock, AV blocks, symptomatic bradycardia, sinus bradycardia with sinus node dysfunction, hypersensitivity

Question 21

Amiodarone Hydrochloride - MoA

Answer 21

Decreases sinus automaticity, reduces the speed of conduction (-dromotropy), increases the refractory period of the AV node, prolongs the action potential duration in all cardiac tissue

Question 22

Amiodarone Hydrochloride - Pharmacokinetics

Answer 22

Onset- 1-30min, Duration- 1-3hrs

Question 23

Amiodarone Hydrochloride - Reactions

Answer 23

Hypotension, bradycardia, prolonged PR interval, pulmonary toxicity. May react with warfarin (Coumadin®), quinidine, digoxin, procainamide and phenytoin

Question 24

Amiodarone Hydrochloride - Dosage

Answer 24

Adult: 150 mg SLOW IVP over 10 mins for JT, MAT, Stable wide complex tachycardia, may repeat once. 300 mg rapid IVP for pulseless VF or VT
Peds: Safety and efficacy not established