Monday - Diebel - Intro to viral skin infections

Question 1

Alpha - herpesviruses

Answer 1

1 - symplex virus 1 - Mouth or pharynx, above waist
2 - symplex virus 2 - genitals, below the waist
3 - Vercilla zoster (VZV) - Chicken pox

latent in neurons

Question 2

Beta - herpesviruses

Answer 2

5 - Human cytomegalovirus
6 & 7 - roseolovirus

T - cells

Question 3

Gamma - herpesviruses

Answer 3

4 - epstein barr (lymphocryptovirus)
8 - kaposi sarcoma-associated virus

B cells

Question 4

This virus doesn’t integrate into the human genome, but infections last a lifetime, and can cause rashes, encephalitis, and lymphoma.

what is it?
characteristics?

Answer 4

Herpesvirus

dsDNA, Group I

enveloped

Question 5

Viral proteins are presented on MHC I receptors. What types of cells recognize these receptors and mediate the killing of the infected cell?

Answer 5

CD8+ T cell

Question 6

Cellular and genomic characteristics of herpesvirdae classes of viruses

Answer 6

dsDNA, group 1 virus

Question 7

Cellular and genomic characteristics of Poxvirus class of viruses

Answer 7

dsDNA, group 1,

Question 8

What causes hand foot and mouth disease? Characteristics of the virus and disease?

Answer 8

Picornaviruses. (coxsackie virus, and to a lesser extent echovirus).

ssRNA (+), Group IV

hands feet and mouth rashes in kids

Question 9

What classes of viruses cause maculopapular rashes?

Answer 9

1,3,5,6

The odds plus six

Question 10

What causes Rubeola? Characteristics of the virus and disease?

Answer 10

Measles virus

ssRNA (-), Group V

respitory system to lymphnodes to blood. skin rash, rare: encephalitis

Question 11

What causes Rubella (german measles)? Characteristics of the virus and disease?

Answer 11

Rubella virus

ssRNA (+), Group IV

mucosal surfaces to lymphnode to blood. can cause congenital defects.

Question 12

What causes Fifths diesease? Characteristics of the virus and disease?

Answer 12

Parvovirus B19

ssDNA, group II

also called erythema infectiosum, slapped-cheek appearance, very mild but contagious. can cause abortion in first trimester.

Question 13

What causes a high fever (up to 105F, 41C) in kids that comes on quickly, lasts for up to three days, and dissapears on the fourth day (at this point a rash can appear). Also thought to be in 100% of the adult population?

Answer 13

Roseola, or sixth disease

Question 14

HPV. Characteristics of the virus and disease? treatement and diagnosis?

Answer 14

Human papilloma virus.

dsDNA, group I

warts - tumorigenic - carcinomas (cervical cancer)
direct contact DTD

PCR can screen for it (women over 30). incurable