Molecular Genetics Flashcards

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1
Q

Griffith

A

mice, bacteria strains

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2
Q

Avery

A

figured out the transforming factor was DNA

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3
Q

Hershey and Chase

A

used bacteriophages to support previous claims

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4
Q

Watson and Crick

A

structure of DNA

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5
Q

Chargaff

A

base pairing rules (C-G, etc)

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6
Q

What 3 things make up nucleotides?

A
  1. Five-carbon sugar (deoxyribose)
  2. Phosphate group
  3. Nitrogenous base
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7
Q

How many amino acids are there?

A

20 different kinds

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8
Q

Helicase

A

unwind, unzip DNA, break hydrogen bonds

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9
Q

Topoisomerase

A

relaxes DNA; loosen it up

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10
Q

RNA primase

A

10 RNA bases

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11
Q

DNA polymerase

A

add new nucleotides, proofread bases, fix minor errors (same)

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12
Q

RNA polymerase

A

add new nucleotides, proofread bases, fix minor errors (same)

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13
Q

DNA ligase

A

connections okazaki fragments

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14
Q

Semiconservative

A

saves 1/2 the DNA

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15
Q

Transcription

A

converting from DNA to RNA

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16
Q

Translation

A

decoding DNA’s message to make proteins

17
Q

DNA vs RNA

A

-DNA is double stranded
-RNA is single stranded
-DNA base called thymine
-RNA base called uracil
-DNA deoxyribose sugar
-RNA ribose sugar

18
Q

mRNA

A

carries DNA message

19
Q

tRNA

A

carries amino acids

20
Q

rRNA

A

makes ribosomes

21
Q

Amino acids are the building blocks of ____?

A

proteins

22
Q

Types of mutations

A

Frameshift:
-Addition/insertion
-Deletion
Nonsense: early stop codon
Missense (substitution)- change in amino acid
Silent: no change