Molecular Biology Flashcards
Gene
An entire nucleic acid sequence, including non transcribed regulatory sequences (e.g promoters and splice and poly (A) sites) that is necessary for the synthesis of a functional molecule in the right place
Classes of eukaryotic DNA
1) protein coding genes
2) tandemly repeated genes
3) repetitive DNA
4) unclassified spacer DNA
Heterochromatin
Chromatin regions that do not uncoil
Chromatin remodeling complexes
Chromatin remodeling complexes are large protein machines that use ATP hydrolysis to open the structure of condensed chromatin or to re-condense chromatin in
The histone code hypothesis
Distinct markings of the histone tails facilitate the recruitment of distinct protein complexes that mediate transcriptional activation or inactivation, efficient repair of genetic lesions and mark newly replicated chromatin
Antigenicity
Virus ability to causes an immune response
Haemagglutinin
Major envelope protein involved in the fusion of the viral envelope with the host cell membrane. Major target for neutralizing antibodies
Neuraminidase
Tetrameric spike that projects from the surface and removes sialic acid from glycoproteins