Mohs Boards Flashcards

You may prefer our related Brainscape-certified flashcards:
1
Q

Biological to treat DFSP

A

Imatinib

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Immunostain used in Mohs to identify SCC

A

AE1/AE3

Also called pan cytokeratin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Ber-EP4

A

BCC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

AE1/AE3

A

Pancytokeratin stains

BCC and SCC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

MN116

A

BCC and SCC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

CD34

A

DFSP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Immunostain for DFSP

A

CD34

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

CK7

A

Extramamary Paget’s disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Immunostain stain for Extramammary Pagets

A

CK7

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

HMB-45

A

Immunostain for Melanoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

SOX10

A

Immunostain stain for melanoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Name the common immunostain a for melanoma

A

MART1/Melan A
HMB45
SOX10
S100

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Immunostain for Merkel Cell Carxinoma

A

CK20

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

CK20

A

Immunostain for Merkel Cell Carcinoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Cam5.2(low molecular weight cytokeratin)

A

Mutinous Carcinoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Immunostain for Mucinous Carcinoma

A

Cam5.2 (low molecular weight cytokeratin)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Exposure to mineral oil weirdly causes what cancer

A

bcc

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Exposure to soot weirdly causes what type of cancer

A

BCC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Most common cancer to arise within bcc

A

Trichiblastoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Name some MOA of retinoids

A
Inhibits ornithine decarboxylase
Inhibits collagenase 
Downregs proliferative keratins K6/K16
Increases fillagrin 
Increases keratin filaments
Antagonizes function of AP-1 and IL-6
Downregulates TLR 2
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

anesthetic shortest duration

A

procaine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

anesthetic risk of fetal bradycardia

A

mepivacain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

anesthetic risk of methemoglobinemia

A

prilocaine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

anesthestic longest duration with epi

A

bupivacaine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

anesthetic with cardiac toxicity

A

bupivacaine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

anesthetic with most rapid onset

A

chloroprocaine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

anesthetic with longest overall duraction

A

ropivacaine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

surgical prep w most rapid onset

A

alcohol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

what is the only organism alcohol Surg prep doesn’t cover for?

A

spores

30
Q

what is the antiseptic with the longest duration of action?

A

chlorhexadine

31
Q

what does chlorhexidine not cover for?

A

pseudomonas

32
Q

which Surg prep is effective against spores?

A

iodine

33
Q

which Surg prep must wait to dry to be effective?

A

iodine

34
Q

what is iodine inactivated by?

A

blood, serum

35
Q

what Surg prep is neurotoxic to infants?

A

hexochlorophene

36
Q

what is the worst antiseptic of all?

A

triclosan

37
Q

minocycline hyper pig type I

A

in scars

38
Q

minocycline hyperpigmentation type ii

A

arms and legs

39
Q

minocycline hyperpigmentation type III

A

sun exposed areas like head

40
Q

what does minocycline stain with on path

A

melanin (Fontana Mason) and iron (Perls)

41
Q

5-FU MOA

A

inhibits thymidyline synthetase

42
Q

what inhibits thymidyline synthetase

A

5 - FU

43
Q

what drug to add to drabafinib (BRAF inhibitor) to stop the occurrence of SCCs as a side effect?

A

Trametinib ( a MEK inhibitor)

44
Q

Mel marker calcium binding protein

A

S100

45
Q

Melanoma marker is part of a gp100 complex

A

HMB-45

46
Q

Melanoma marker is a transcription regulated of the tyrosinase gene

A

MITF-1

47
Q

Melanoma marker is a transcription factor/SRY related HMG box protein

A

SOX-10

48
Q

Melanoma marker is a melanocytes differentiation antigen (transmembrane protein)

A

MART-1

49
Q

Ferguson Smith

A

TBG-B

Large KA syndrome

50
Q

Rothmund Thompson

A

REQL4

51
Q

Dystrophic EB

A

Collagen type VII

52
Q

SCC gene mutations

A

p53
NOTCH
Rad

53
Q

EDV

A

HPV 5,8,47

54
Q

Bowenoid papulosis

A

HPV 16

55
Q

Verrucous carcinoma

A

HPV 6,11,16,18

56
Q

Familial Melanoma

A

CDKN2a

57
Q

What are the protein products in CDKN2a melanoma?

A

P53 (chromosome p14) and Rb (p16)

58
Q

Ocular melanoma

A

BAP

59
Q

Gene for pigmentation and melanoma

A

MITF

60
Q

60% of melanoma cases are what gene

A

BRAF

61
Q

Melanoma gene for INTERMITTANT sun exposure

A

BRAF

62
Q

Melanoma gene for CHRONIC sun exposure

A

NRAS

63
Q

Uveal melanoma

A

GNAQ

64
Q

Blue nevi

A

GNAQ

65
Q

NRAS

A

Melanoma of CHRONIC exposed skin

66
Q

BAPoma for ocular melanoma and what other kind of cancer

A

Mesothelioma and renal cell carcinoma

67
Q

TGB-1 gene

A

Ferguson Smith

68
Q

PDGF-B and Col-1 fusion gene

A

DFSP

On chromosome 7,11

69
Q

What is the specific gene mutation for BRAF

A

Mutation of glutamine (E) for valine (V) at V600

70
Q

Familial melanoma CDKN2A risk of what other type of cancer

A

Pancreatic