Module 6: Amino Acids and Proteins Obj. 2 Flashcards
3 main classifications of proteins
Simple
Conjugated
Derived
Simple proteins
contain only 1 amino acid
Hydrolysis of a simple protein yields only amino acids
Ex. albumin, some globulins, scleroproteins (hair, nails) and collagens
Conjugated Proteins
Hydrolysis eyelids amino acids plus a non-protein prosthetic group which is essential to the function of the protein
If prosthetic group is removed, remaining protein is called an apoprotein
Ex. Conjugated protein: chromoprotein (Hb), prosthetic group: chromophore (heme)
Derived proteins
breakdown products of proteins
ex. peptones, peptides
4 levels of protein structure and bonds used in each
Primary
secondary
tertiary
quaternary
Primary structure
attachment together of many amino acids in polypeptide chains bound together by PEPTIDE BONDS
Sequencing is determined by genetic coding
Secondary structure
shaping of polypeptides by HYDROGEN BONDING into alpha helix or beta pleated sheet or random coil structure
Tertiary structure
folding of polypeptide chain into a characteristic 3D structure under influence of hydrogen bonds, COVALENT BONDS, IONIC BONDS and HYDROPHILIC BONDS
Quaternary structure
sub-unit association
The bonding together of several folded polypeptide chains into specific layers, crystals or fibers
Prosthetic groups may be added at this time
Ex. heme added to globin