Module 6 Flashcards
What is evidence based practice (EBP)?
- EBP is the integration of best available research with clinical expertise in the context of the client
- Start with client and apply research evidence
- Not EB treatment (starts with treatment, used until 90s)
- EBP can be operationalised as a combination of 3 factors inside the context of practice:
- Best research evidence
- Clinical expertise (tacit and explicit)
- Client values, characteristics, preferences)
What is the 6-step process of EBP?
- Assess your patient; Define the problem, gather information regarding client history, distress, etc
- Ask the right question; What are you looking for? Have clients expressed a preference or aversion for a particular treatment?
- Assess the evidence; What is the current empirical support?
- Appraise the evidence; Critically analyse the research
- Apply the evidence; Consider the evidence in relation to the client circumstances (cultural, personal factors etc)
- Audit clinical practice; reflect on practice and modify what is and isnt effective
What is the NHMRC heirachy of evidence?
- I: Systematic review of RCTs
- II: At least one RCT
- III-1: Well designed pseudo RCT
- III-2: Comparative studies with current controls, cohort study
- III-3: Comparative studies with historical control, 2-arm studies
- IV: Case studies
How can we define best research evidence (in RCTS)?
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Best evidence involves RCTs which show:
- Statistical significance
- Clinical significance
- Reasonable effect sizes
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Characteristics of RCTs:
- Primarily medical model
- Involve large sample sizes (issues with dropouts and small effect sizes)
- Randomisation balances variance due to extraneous variables
What are some sources of research evidence?
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Cochraine Collaboration;
- Produces highest standard systematic reviews in health care
- PICO (participants, interventions, comparisons, outcomes)
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National Institute for Clinical Evidence
- Produces standards of excellence (short, evidence based statements for practitioners)
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World Health Organisation
- Publishes systematic reviews
- Note context roles (cost of studies are often a barrier in non-western countries)
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Moriana, Galvaz-Lara, Corpasa Review
- Recent review of standards of evidence across organisations incl APS, NICE, Cochraine. Noted inconsitencies
What are some limitations to the EBP model?
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Critiques of Evidence Based Medicine Model
- David Healy; criticism of role of bias in evidence based medicine, particularly BigPharma in SSRI research
- Effects of funding, publication bias and mishandling of data
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Dodo effect; there is evidence that no form of psychological treatment is actually any more beneficial than another
- Common factors
- Problem when considering harmful side effects of aversive techniques
What is Practice-Based Evidence (PBE)?
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Evidence of efficacy is generated by the practitioner rather than the treatment framework (a bottom up rather than top down approach)
- Recent response to backlash against trustworthiness of observer led approach of EBP
- Based on asking psychologists to employ universal outcome measures to allow systematic comparison
- Health of the Nation Outcome Scales (HoNOS): 12-item likert scale (score out of 48). Rated at end of each session.
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Clinical Implications:
- Therapy should be collaborative, weight cost vs benefits
- Client should be informed, evolved and consulted in treatment plan
What are POR and PRN?
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Practice Oriented Research (POR) or practice-based research
- Conducting research in a routine practice setting (naturalistic)
- Research conducted with a group not on a group
- Provides opportunities for 2way learning
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Practice Reseach Networks (PRN)
- Developed to enable smooth trasition from research to practice
- Collaborative enterprise between students, faculties, clinicians, administrators etc
- eg Centre for Collegiate Mental Health
What potential approaches of the Science-practitioner model are outlined in Stricker (2002)?
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Local Clinical Science Model (LCS): Define science as an attitude carried into clinical practice (critical inquiry)
- Question, Apply findings, Reflect, Produce research
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Systematic Treatment Selection (STS); distinguish effective parts of treatments and apply them systematically to individual patients
- Combine approaches to tailor treatment
- Caveat; few practitioners equally strong in all areas, practice in same way
- Patient Focused Research; Focus on progression of treatment for individual client, tracking progress relative to similar clients
- Psychotherapy Integration; Umbrella concept, consumate example of SP thinking. Struggles with actualization due to clash of manualisation and flexibility requirements.
- Practitioner-Initated Research; Context of discovery (usually practioners) vs context of confirmation (usually researchers). Focus on fostering connection between the two.
- Practice Informed Research; Regardless of primary interest, effectiveness is more important than efficacy. Clinical outcomes are primary concern,
What reasons did Moriana et al (2017) suggest for discrepencies between levels of treatment evidence across organisations?
- High levels of disagreement: Only 4 disorders had excellent agreement (GAD, phobias, Bulimia, OCD), 3 good agreement (Anorexia, Schiz, ADHD)
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Potential causes:
- Bias in procedures/committees: information not provided for ineffective treatments, bias to own studies
- Different RCTs, meta-analysis reviewed; particularly for BPD and schizophrenia
- Different criteria on what consititutes effective
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Limitations of study:
- Heterogeneity of levels of evidence hinders comparisons
- Only compared 4 international organisations
- Only examined a small proportion of disorders
What 9 foci do Homlqvest et al outline as arguments for practice-based studies?
- Patients; Many clients have more complex and heterogenous situations than are captured in research settings
- Therapists; Often have heterogenous competences, trained in combinations of multiple approaches
- Treatment length; Actual practice duration may differ significantly from manual recomendations
- Under-represented treatments; Non-manualised treatments are rarely studied in RCTs.
- Therapist effects and training; Therapists in RCTs controlled for training level and background
- Patient-treatment matching; Assigning a patient to a treatment based on personal factors may be different to randomising
- Dropouts; Include dropouts as an outcome measure in routine practice dropout rates are high.
- Service effects: examine differences in delivery context (not controlled)
- Benefits for clinicians: May find feedback more useful
What challenges do Holmqvist et al identify for practice-based studies?
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Therapist participation rates:
- Concern over increased administrative demands, difficulty in defining “therapeutic” interactions, what feedback would be obtained.
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Being fit for purpose and fitting the political space
- Balancing measures that are useful for research and practitioners, but also adheres to political requirements around health delivery (over-valuing symptom specific outcomes)
- Empirical and conceptual mapping; How to best map and examine ther relationships between different outcome measures
What is the Neremberg Code?
- Set of principles for human research finalised during the Nuremberg Trials. 10 Principles:
- Voluntary consent of participant
- Experiment is justified
- Experiment designed with knowledge of area
- Avoid all unnecessary suffering/injury
- Never conduct an experiment with forseeable risk of death or disablement (except maybe on self)
- Risk should never exceed benefits
- Ensure adequate protection for subject even for low risk
- Only scientifically qualified persons may conduct experiment
- Subject free to leave at any time
- Scientist prepared to end experiement immediately if there is risk
What are some of the strengths and limirtations of the Nuremberg Code?
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Strengths and significance:
- A turning point in medical and biological research
- Underlying values of justic, respect and informed consent first articulated
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Limitations:
- Origin led many to believe it to have nothing to teach non-nazi physicians
- Over-emphasis on informed consent at expense of other principles
- Incomplete guidance
What is the Declaration of Helsinki?
- Official policy document of the World Medical Association
- First developed in 1964, from similar circumstances to the Nuremberg Code
- Regularly updated, most widely known and available guideline, scope beyond human concerns
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Ashmond Controversy surrounding recent versions
- Debate of ethical authority of declaration, and of the WMA to regulate worldwide
- Concerns over impractical requirements in resource-poor settings
- Inconsistencies and undue restrictions/biases
- Has become politicised
- No explanatory notes or discussion points, reliance on interpretation is risky