Module 5 EoC Questions Flashcards
Common vectors of Lyme disease include all of the following except:
I. pacifucus
I. scapularis
I. ricinus
D. variabilis
D. variabilis
The only continent without lyme disease is
Antarctica
The primary reservoir in nature for B. burgdorferi
white-footed mouse
The first B. burgdorferi antigen to elicit an antibody response is
flagellar 41-kDa polypeptide
Erythema chronicum migrans (ECM)
Harbors B. burgdorferi in the advancing edge
The predominant symptoms of Lyme meningitis are
severe headache and mild neck stiffness
The most useful test for distinguishing between true positive and false positive serologic test results in lyme disease is
polymerase chain reaction
Lyme disease prevention methods include all of the following except:
wearing light-colored clothes
tucking pants into socks
applying insect repellent to skin and clothes
all of the above
All of the above
Lyme disease, the most common ttick-borne disease in the United States, is a major health hazard for:
dogs
horses and cattle
humans
all of the above
all of the above
lyme disease is a ___ type of infection
bacterial
Unlike some procedures, the polymerase chain reaction assay can be used to detect lyme disease-causing organisms in
synovial
Antigen detection systems in Lyme disease testing screen for ____ rather than for ____ associated with the infection
antigenic products (1)
antibody (2)
A patient who has a specific Lyme disease-associated manifestation may be treated with
antibiotic
West Nile virus causes
encephalitis
A type 1 hypersensitivity reaction is a
anaphylactic reaction
A type 2 hypersensitivity reaction is a
cytotoxic reaction
A type 3 hypersensitivity reaction is a
immune complex reaction
A type 4 hypersensitivity reaction is a
cell-mediated reaction
with which cell type are anaphylactic reactions associated
mast
type 3 reactions are exemplified by all of the following except:
arthus reaction
serum sickness
glomerulonephritis
shingles
shingles
Type 4 reactions are responsible for all of the following except:
contact sensitivity
delayed hypersensitivity
elimination of tumor cells bearing neoantigens
hemolysis of red blood cells
hemolysis of red blood cells
Type 1 hypersensitivity reactions can be associated with:
food allergies
hay fever
asthma
all of the above
all of the above
The most common agents that cause anaphylactic reactions are
drugs and insect stings
An example for a delayed nonhemolytic (type 2 hypersensitivity) reaction is
graft-versus-host disease
All of the following characteristics are common to organ-specific and organ-nonspecific disorders except:
autoantibody tests are of diagnostic value
antibodies may appear in each of the main immunoglobulin classes
antigens are available to the lymphoid system in low concentrations
circulatory autoantibodies react with normal body constituents
antigens are available to the lymphoid system in low concentrations
antibody expression in the development of autoimmunity is regulated by all of the following factors except:
genetic predisposition
increasing age
environmental factors
active infectious disease
active infectious disease
the mechanisms responsible for autoimmune disease is
circulating immune complexes
one of the mechanisms of self-tolerance is
elimination of self-reactive immature lymphocytes
A characteristic associated with anticardiolipin antibody is
present in SLE and associated with arterial and venous thrombosis
A characteristic associated with anti-DNA antibodies is
useful in monitoring the activity and exacerbations of SLE
The term autoimmune disease is used when
demonstrable immunoglobulins display specificity for self antigens
cytotoxic T cells display specificity for self antigens
cytotoxic t cells contribute to the pathogenesis of the disease
all of the above
all of the above
a description of antinuclear antibody (ANA) is
a characteristic of untreated systemic lupus erythematosus
SLE is more common in
adolescent through middle-aged women
one of the most potent inducers of abnormalities and clinical manifestations of SLE is
procainamide hydrochloride
The principal demonstrable antibody in SLE is antibody to
nuclear antigen
SLE is a classic model of autoimmune disease and is a(n):
abnormality of the joints
systemic rheumatoid disorder
abnormality of connective tissue
all of the above
all of the above
The overall incidence of SLE has an increased frequency among:
african americans
native americans
puerto ricans
all of the above
all of the above
patients with SLE characteristically manifest
butterfly rash over the bridge of the nose
Laboratory features of SLE include:
the presence of ANAs
circulating anticoagulant and immune complexes
decreased levels of complement
all of the above
all of the above
Laboratory procedures that are helpful in assessing renal disease include:
antibody to double-strand DNA
levels of C3 and C4
cryoglobulin assay
all of the above
all of the above
The ANA staining of a diffused or homogenous pattern is associated with
anti-dna-nucleoprotein antibody
the ANA staining of a speckled pattern is associated with
antibody to any extractable nuclear antigen devoid of DNA or histone
Rheumatoid arthritis most frequently develops in
middle-aged women
rheumatoid factor is defined as
antibodies with specificity for antigen determinants on of Fc fragment of human or certain animal IgG
The principle of the rapid agglutination test is based on the reaction of patient ___ and ___ derived from gamma globulin
antibody
antigen
Criteria for the diagnosis of rheumatoid arthritis include
morning stiffness
rheumatoid nodules
radiographic changes
all of the above
all of the above
RF correlates with all of the following except:
the severity of the disease in general
the presence of nodules
other organ system involvement
the age of the patient
the age of the patient
