Module 5 EoC Questions Flashcards

1
Q

Common vectors of Lyme disease include all of the following except:

I. pacifucus
I. scapularis
I. ricinus
D. variabilis

A

D. variabilis

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2
Q

The only continent without lyme disease is

A

Antarctica

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3
Q

The primary reservoir in nature for B. burgdorferi

A

white-footed mouse

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4
Q

The first B. burgdorferi antigen to elicit an antibody response is

A

flagellar 41-kDa polypeptide

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5
Q

Erythema chronicum migrans (ECM)

A

Harbors B. burgdorferi in the advancing edge

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6
Q

The predominant symptoms of Lyme meningitis are

A

severe headache and mild neck stiffness

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7
Q

The most useful test for distinguishing between true positive and false positive serologic test results in lyme disease is

A

polymerase chain reaction

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8
Q

Lyme disease prevention methods include all of the following except:

wearing light-colored clothes
tucking pants into socks
applying insect repellent to skin and clothes
all of the above

A

All of the above

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9
Q

Lyme disease, the most common ttick-borne disease in the United States, is a major health hazard for:

dogs
horses and cattle
humans
all of the above

A

all of the above

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10
Q

lyme disease is a ___ type of infection

A

bacterial

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11
Q

Unlike some procedures, the polymerase chain reaction assay can be used to detect lyme disease-causing organisms in

A

synovial

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12
Q

Antigen detection systems in Lyme disease testing screen for ____ rather than for ____ associated with the infection

A

antigenic products (1)

antibody (2)

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13
Q

A patient who has a specific Lyme disease-associated manifestation may be treated with

A

antibiotic

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14
Q

West Nile virus causes

A

encephalitis

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15
Q

A type 1 hypersensitivity reaction is a

A

anaphylactic reaction

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16
Q

A type 2 hypersensitivity reaction is a

A

cytotoxic reaction

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17
Q

A type 3 hypersensitivity reaction is a

A

immune complex reaction

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18
Q

A type 4 hypersensitivity reaction is a

A

cell-mediated reaction

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19
Q

with which cell type are anaphylactic reactions associated

A

mast

20
Q

type 3 reactions are exemplified by all of the following except:

arthus reaction
serum sickness
glomerulonephritis
shingles

A

shingles

21
Q

Type 4 reactions are responsible for all of the following except:

contact sensitivity
delayed hypersensitivity
elimination of tumor cells bearing neoantigens
hemolysis of red blood cells

A

hemolysis of red blood cells

22
Q

Type 1 hypersensitivity reactions can be associated with:

food allergies
hay fever
asthma
all of the above

A

all of the above

23
Q

The most common agents that cause anaphylactic reactions are

A

drugs and insect stings

24
Q

An example for a delayed nonhemolytic (type 2 hypersensitivity) reaction is

A

graft-versus-host disease

25
Q

All of the following characteristics are common to organ-specific and organ-nonspecific disorders except:

autoantibody tests are of diagnostic value
antibodies may appear in each of the main immunoglobulin classes
antigens are available to the lymphoid system in low concentrations
circulatory autoantibodies react with normal body constituents

A

antigens are available to the lymphoid system in low concentrations

26
Q

antibody expression in the development of autoimmunity is regulated by all of the following factors except:

genetic predisposition
increasing age
environmental factors
active infectious disease

A

active infectious disease

27
Q

the mechanisms responsible for autoimmune disease is

A

circulating immune complexes

28
Q

one of the mechanisms of self-tolerance is

A

elimination of self-reactive immature lymphocytes

29
Q

A characteristic associated with anticardiolipin antibody is

A

present in SLE and associated with arterial and venous thrombosis

30
Q

A characteristic associated with anti-DNA antibodies is

A

useful in monitoring the activity and exacerbations of SLE

31
Q

The term autoimmune disease is used when

demonstrable immunoglobulins display specificity for self antigens
cytotoxic T cells display specificity for self antigens
cytotoxic t cells contribute to the pathogenesis of the disease
all of the above

A

all of the above

32
Q

a description of antinuclear antibody (ANA) is

A

a characteristic of untreated systemic lupus erythematosus

33
Q

SLE is more common in

A

adolescent through middle-aged women

34
Q

one of the most potent inducers of abnormalities and clinical manifestations of SLE is

A

procainamide hydrochloride

35
Q

The principal demonstrable antibody in SLE is antibody to

A

nuclear antigen

36
Q

SLE is a classic model of autoimmune disease and is a(n):

abnormality of the joints
systemic rheumatoid disorder
abnormality of connective tissue
all of the above

A

all of the above

37
Q

The overall incidence of SLE has an increased frequency among:

african americans
native americans
puerto ricans
all of the above

A

all of the above

38
Q

patients with SLE characteristically manifest

A

butterfly rash over the bridge of the nose

39
Q

Laboratory features of SLE include:

the presence of ANAs
circulating anticoagulant and immune complexes
decreased levels of complement
all of the above

A

all of the above

40
Q

Laboratory procedures that are helpful in assessing renal disease include:

antibody to double-strand DNA
levels of C3 and C4
cryoglobulin assay
all of the above

A

all of the above

41
Q

The ANA staining of a diffused or homogenous pattern is associated with

A

anti-dna-nucleoprotein antibody

42
Q

the ANA staining of a speckled pattern is associated with

A

antibody to any extractable nuclear antigen devoid of DNA or histone

43
Q

Rheumatoid arthritis most frequently develops in

A

middle-aged women

44
Q

rheumatoid factor is defined as

A

antibodies with specificity for antigen determinants on of Fc fragment of human or certain animal IgG

45
Q

The principle of the rapid agglutination test is based on the reaction of patient ___ and ___ derived from gamma globulin

A

antibody

antigen

46
Q

Criteria for the diagnosis of rheumatoid arthritis include

morning stiffness
rheumatoid nodules
radiographic changes
all of the above

A

all of the above

47
Q

RF correlates with all of the following except:

the severity of the disease in general
the presence of nodules
other organ system involvement
the age of the patient

A

the age of the patient