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Serology > End of chapter questions (2) > Flashcards

End of chapter questions (2) Flashcards

1
Q

Digestion of bacteria

A

Second

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2
Q

Increase in chemoattractants at site of tissue damage

A

Fourth

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3
Q

Ingestion of bacteria

A

Third

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4
Q

Change in direction of movement due to a chemoattractant substance

A

First

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5
Q

The function of polymorphonuclear neutrophil (PMN) leukocytes is:

A

Primary phagocytic cells

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6
Q

Mast cells are associated with

A

Participation in IgE hypersensitivity reactions

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7
Q

Chronic granulomatous disease represents a defect of

A

Oxidative metabolism

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8
Q

An alteration of phagocytic killing is associated with

A

Corticosteroid therapy

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9
Q

Mast cells have:

A

High concentration of histamine in the granules

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10
Q

Cell mediated immune response associated with humoral immunity

A

Defense against viral and bacterial infection
Defense against fungal and bacterial infection
Antibody production

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11
Q

T cell functions

A

Mediation of delayed-hypersensitivity reactions
Mediation of cytolytic reactions
Regulation of the immune response

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12
Q

T cell response is associated with

A

Cellular immune response

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13
Q

The function of B cells is

A

Humoral response

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14
Q

NK function

A

Antibody-dependent, cell-mediated cytotoxicity (ADCC) reaction

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15
Q

NK cells mediate

A

viral immunity

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16
Q

Surface membrane marker for CD4

A

Helper-inducer T cells

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17
Q

The surface membrane marker for CD8 is

A

Suppressor-cytotoxic T cells

18
Q

Surface membrane marker for CD3 is

A

All or most T lymphocytes

19
Q

The process of aging causes the thymus to

A

Decrease in size
Lose cellularity

20
Q

T lymphocytes can also be referred to as

A

Memory cells

21
Q

T lymphocyte characteristics

A

Can form a suppressor-cytotoxic subset
Can be helper-inducers
Can be CD4+ or CD8+

22
Q

T lymphocyte immune response it’s associated with

A

Cellular immune response

23
Q

B lymphocytes are associated with what immunity

A

Humoral antibody response

24
Q

The appropriate function of cytotoxic or effector T cells is related to/associated with

A

Directly destroying target cells
Transplanted organ rejection
CD4+ marker

25
Q

Regulator T cell function

A

Activate macrophages
Stimulate cell growth and differentiation
Antibody production and secretion of cytokines

26
Q

The complement system is

A

A heat-labile series of plasma proteins
Composed of many proteinases
Composed of three interrelated pathways

27
Q

All of the following are complement-controlling proteins except:

C1 (INH)
Factor I
Factor H
C3

A

C3

28
Q

The three complement activation pathways converge at the point of cleavage of complement component

A

C3

29
Q

All of the following result from complement activation except:

Decreased cell susceptibility to phagocytosis
Blood vessel dilation and increased vascular permeability
Production of inflammatory mediators
Cytolysis or hemolysis

A

Decreased cell susceptibility to phagocytosis

30
Q

Which complement component is present in the greatest quantity in plasma

A

3

31
Q

Classic complement activation sequence

A

C1 to C4 to C2 to C3 to C5 to C6789

32
Q

Arrange the three stages of the classic complement pathways in the correct sequence

A

Recognition
Enzymatic activation
Membrane attack

33
Q

At what stage does the complement system reach its full amplitude

A

C3

34
Q

What makes up the membrane attack complex

A

C5b6789

35
Q

The final steps (C8 and C9) in complement activation lead to

A

Cell lysis

36
Q

Activation by antigen-antibody complexes represents

A

Classic pathway

37
Q

Generation of an active (C3b, Bb) C3 convertase is seen in

A

Alternative pathway

38
Q

Activation by microbial and mammalian cell surfaces occurs in

A

Alternative pathway

39
Q

The ____ terminates in a membrane attack complex

A

Classic and alternative pathway

40
Q

The alternative complement pathway is (can be):

A

Considered to be a predominantly, non-antibody-initiated pathway
Activated by factors such as endotoxinbs

Serology (7 decks)

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