Module 4: Nephrotoxicity and Nephrotoxic medications

Question 1

What is nephrotoxicity?

Answer 1

Nephrotoxicity refers to the toxic effect of substances on the kidneys, leading to impaired kidney function.

Question 2

True or False: Nephrotoxicity can result from both medications and environmental toxins.

Answer 2

True

Question 3

Fill in the blank: Common signs of nephrotoxicity include ______ and ______.

Answer 3

increased serum creatinine, decreased urine output

Question 4

Which class of medications is commonly associated with nephrotoxicity: A) Antibiotics B) Antihistamines C) Antidepressants?

Answer 4

A) Antibiotics

Question 5

Name two examples of nephrotoxic medications.

Answer 5

Aminoglycosides and Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)

Question 6

True or False: All patients taking nephrotoxic drugs will develop kidney damage.

Answer 6

False

Question 7

What is the primary mechanism of nephrotoxicity for aminoglycosides?

Answer 7

Aminoglycosides primarily cause nephrotoxicity through renal tubular cell damage.

Question 8

Multiple choice: Which of the following is NOT considered nephrotoxic? A) Vancomycin B) Acetaminophen C) Cisplatin

Answer 8

B) Acetaminophen

Question 9

Short answer: How can nephrotoxicity be monitored in patients?

Answer 9

By regularly checking kidney function tests such as serum creatinine and urine output.

Question 10

Fill in the blank: ______ is a common nephrotoxic agent used in chemotherapy.

Answer 10

Cisplatin