Module 4 (CONNECTIVE TISSUE) Flashcards

1
Q

most abundant and most widely distributed tissue in the body

A

CONNECTIVE TISSUE

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2
Q

consists of three basic elements : cells, ground substance, and fibers

A

CONNECTIVE TISSUE

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3
Q

CONNECTIVE TISSUE three basic elements

A

cells, ground substance, and fibers

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4
Q

connective tissue cells are separated by considerable amount of matrix

A

CONNECTIVE TISSUE

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5
Q

do not usually occur on free surfaces

A

CONNECTIVE TISSUE

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6
Q

has nerve supply except for cartilage

A

CONNECTIVE TISSUE

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7
Q

highly vascular except cartilage, tendons have scanty blood supply

A

CONNECTIVE TISSUE

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8
Q

matrix maybe fluid, semi-fluid, gelatinous or calcified. *which is usually secreted by the connective tissue cells and adjacent cells and determines the tissue quality; in blood, the matrix is fluid.

A

CONNECTIVE TISSUE

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9
Q

binds, supports and strengthens other body tissues
protects and insulates internal organs

A

CONNECTIVE TISSUE

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10
Q

compartmentalizes structures such as skeletal muscles

A

CONNECTIVE TISSUE

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11
Q

major transport system within the body

A

blood

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12
Q

a fluid from the connective tissue

A

blood

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13
Q

major site of stored energy reserves

A

adipose (fat) tissue

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14
Q

derived from embryonic mesodermal cell called mesenchymal cells

A

CONNECTIVE TISSUE CELLS

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15
Q

most common cells in the connective tissue

A

FIBROBLASTS

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16
Q

responsible for the synthesis of extracellular matrix components (including proteins, such as collagen and elastin.

A

FIBROBLASTS

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17
Q

large, flat, spindle-shaped with branching processes

A

FIBROBLASTS

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18
Q

targets of various growth factors. *that influence cell growth and differentiation

A

FIBROBLASTS

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19
Q

TWO STAGES OF ACTIVITY
OF FIROBLASTS

A

Active
Quiescent

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20
Q

with intense synthetic activity

A

Active cell

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21
Q

Has an abundant and irregularly branched cytoplasm. Nucleus is ovoid, pale-staining, with fine chromatin and a prominent nucleolus. The cytoplasm is rich in rough ER and the golgi apparatus is well developed

A

Active cell

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22
Q

scattered within the matrix where they are already synthesized

A

Quiescent cell

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23
Q

Smaller than the active fibroblast and is usually spindle shaped. Has a fewer processes; a smlaller, elongated nucleus; and more acidophilic cytoplasm with much less in rough ER.

A

Quiescent cell

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24
Q

DENOTION OF QUIESCENT CELL

A

FIBROCYTE

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25
Q

DENOTION OF ACTIVE CELL

A

fibroblast

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26
Q

discovered and initially characterized by their phagocytic ability.

A

MACROPHAGE

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27
Q

capable of engulfing bacteria and cellular debris by phagocytosis

A

MACROPHAGE

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28
Q

TYPES of MACROPHAGE

A

Wandering
Fixed

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29
Q

leave blood and migrate to infected area

A

Wandering Cell

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30
Q

remain in certain tissues and organs

A

Fixed Cell

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31
Q

are distributed throughout the body and are present in most organs. They comprise a family called “MONONUCLEAR PHAGOCYTE SYSTEM”.

A

Macrophages

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32
Q

All are long-living cells and may survive for months in tissues

A

Macrophages

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33
Q

Monocyte LOCATION and MAIN FUNCTION

A

Blood

Precursor of macrophage

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34
Q

MACROPHAGE LOCATION and MAIN FUNCTION

A

Connective tissue, lymphoid organs, lungs, bone marrow

Production of cytokines, chemotactic factors, and several other molecules that participate in inflammation (defense), antigen processing and presentation

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35
Q

KUPFFER CELL

A

Liver

Same as macrophage

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36
Q

MICROGLIA CELL

A

Nerve tissue of the CNS

Same as macrophage

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37
Q

LANGERHANS CELL

A

Skin

Antigen processing and presentation

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38
Q

DENDRITIC CELL

A

Lymph nodes

Antigen processing and presentation

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39
Q
A
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40
Q

MULTINUCLEAR GIANT CELL

A

Connective tissue (fusion of several macrophages)

Segregation and digestion of foreign bodies

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41
Q

Large, oval or round connective tissue cells, 20-30 um in diameter, whose cytoplasm is filled with basophilic secretory granules.

A

MAST CELLS

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42
Q

Abundant alongside blood vessels

A

MAST CELLS

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43
Q

Produce histamine. *chemical that causes small blood vessels to dilate during inflammation

A

MAST CELLS

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44
Q

Contain heparin to bind certain intracellular contents

A

MAST CELLS

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45
Q

A partial list of important molecules released from Mast Cells

A

Heparin
Histamine
Serine proteases
Eosinophil and neutrophil chemotactic factors

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46
Q

acts locally as an anticoagulant

A

Heparin

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47
Q

promotes increased vascular permeability and smooth muscle contraction

A

Histamine

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48
Q

attract leukocytes

A

Eosinophil and Neutriphil chemotactic factors

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49
Q

Release of chemical mediators stored in mast cells promote the allergic reactions.

A

IMMEDIATE HYERSENSITIVITY REACTION

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50
Q

activate various mediators of inflammation

A

Serine proteases

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51
Q

Large, ovoid cells that have a basophilic cytoplasm due to their richness in rough ER

A

PLASMA CELLS

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52
Q

Nucleus is generally spherical but eccentrically placed.

A

PLASMA CELLS

53
Q

Secrete antibodies. *provide defense mechanism though immunity

A

PLASMA CELLS

54
Q

contains a diversity of large molecules.
Influencing tissue development, migration, proliferation, shape and even metabolic functions

A

ground substance

55
Q

highly hydrated, transparent complex mixture of macromolecules

A

ground substance

56
Q

3 Classes of ground substance

A

Glycosaminoglycans
Proteoglycans
Multiadhesive glycoproteins

57
Q

Originally called mucopolysaccharides

A

GLYCOSAMINOGLYCANS

58
Q

Formed by repeating disaccharide units usually composed of uronic acid and hexosamine

A

GLYCOSAMINOGLYCANS

59
Q

can be galactosamine or glucosamine

A

HEXOSAMINE

60
Q

can be glucuronic or iduronic acid

A

URONIC ACID

61
Q

The largest and most unique GAG

A

hyaluronic acid (or hyaluronan)

62
Q

a viscous substance that binds cells together, lubricates joints, maintain shape of eyeball

A

HYALURONIC ACID

63
Q

Composed of a core protein to which are covalently attached various numbers and combinations of the GAG.

A

PROTEOGLYCANS

64
Q

They are synthesized in RER, mature in the golgi and secreted by cells by exocytosis

A

PROTEOGLYCANS

65
Q

have carbohydrates attached

A

MULTIADHESIVE GLYCOPROTEINS

66
Q

anchor cells in position and provide traction for the movement of cells

A

MULTIADHESIVE GLYCOPROTEINS

67
Q

examples of MULTIADHESIVE GLYCOPROTEINS

A

Fibronectin
Laminin

68
Q

has binding sites for collagen, certain GAGs, and integrins of cell membranes

A

Fibronectin

69
Q

participates in the adhesion of epithelial cells to the basal lamina, also with binding sites. *All basal laminae are rich in _______

A

Laminin

70
Q

Provide strength and support for tissues

A

FIBERS

71
Q

Types of Fibers

A

Collagen fibers
Elastic fibers
Reticular Fibers

72
Q

Very tough and resistant to pulling yet allow some flexibility of the tissue
Occur in bundles made of many tiny fibrils parallel to one an other

A

COLLAGEN FIBERS

73
Q

Consists of protein collagen /9most abundant protein in the body, 25% of total protein)
Found in bones, cartilages, tendons, and ligaments

A

COLLAGEN FIBERS

74
Q

Smaller in diameter than collagen
Branched and joined together to form network within tissue

A

ELASTIC FIBERS

75
Q

Contains protein elastin
Can be stretched upto 150% of their relaxed strength without breaking
Found in skin, blood vessel wall, lung tissue

A

ELASTIC FIBERS

76
Q

Consists of protein collagen and coating of glycoprotein

A

RETICULAR FIBERS

77
Q

Provide support in the walls of blood vessels and form network around fat cells, nerve fibers, skeletal and smooth muscle cells

A

RETICULAR FIBERS

78
Q

Thinner than collagen fibers and form branching networks
Help form the basement membrane

A

RETICULAR FIBERS

79
Q

Types of Connective Tissue

A

Embryonic Connective Tissue
Adult Connective Tissue

80
Q

Types of Embryonic Connective Tissue

A

Mesenchyme
Mucus Connective Tissue

81
Q

Types of Adult Connective Tissue

A

Loose CT (Areolar)
Dense CT
Specialized CT

82
Q

Types of Dense CT

A

Elastic CT
Irregular CT
Regular CT

83
Q

Types of Specialized CT

A

Reticular CT
Adipose CT

84
Q

Primarily present in the embryo or fetus

A

EMBRYONIC CONNECTIVE TISSUE

85
Q

developing human from pregnancy to first two months of pregnancy

A

EMBRYO

86
Q

developing human from third month of pregnancy until birth

A

FETUS

87
Q

irregularly shaped mesenchymal cells embedded in a semifluid ground substance that contains delicate reticular fibers

A

MESENCHYME

88
Q

star-shaped cells embedded in a viscous, jelly-like ground substance that contains fine collagen fibers

A

MUCUS CONNECTIVE TISSUE

89
Q

Location : deep to skin and along developing bones of embryo, some found in adult especially along blood vessels

A

MESENCHYME

90
Q

Function : forms all other kinds of connective tissue

A

MESENCHYME

91
Q

Location : umbilical cord of fetus
Function : support

A

MUCUS CONNECTIVE TISSUE

92
Q

Fibers are loosely woven and has many cells

A

LOOSE CONNECTIVE TISSUE

93
Q

consists of fiber (collagen, elastic, reticular) and several kinds of cells embedded in semi-fluid ground substance

A

AREOLAR CONNECTIVE TISSUE

94
Q

Location : subcutaneous layer of skin, superficial regions of dermis, mucus membranes, blood vessels, nerves and around body organs

A

AREOLAR CONNECTIVE TISSUE

95
Q

Function : strength, elasticity, support

A

AREOLAR CONNECTIVE TISSUE

96
Q

Contains numerous, thicker and densely packed fibers but fewer cells

A

DENSE CONNECTIVE TISSUE

97
Q

matrix looks shiny white, consists of predominantly collagen fibers arranged in parallel bundles, fibroblasts present in rows between bundles

A

DENSE REGULAR CONNECTIVE TISSUE

98
Q

Location : forms tendons, most ligaments and aponeuroses (sheet-like tendons that attach muscle to muscle or muscle to bone) and corneal stroma

A

DENSE REGULAR CONNECTIVE TISSUE

99
Q

Function : provides strong attachments between various structures

A

DENSE REGULAR CONNECTIVE TISSUE`

100
Q

consists of predominantly collagen fibers, few fibroblasts

A

DENSE IRREGULAR CONNECTIVE TISSUE

101
Q

Location : dermis of skin, perichondrium (membrane around cartilage), periosteum (around bone), joint capsules, dura mater (outer membrane of the brain), heart valves, membrane capsules around various organs (kidneys, liver, testes)

Function : provides strength

A

DENSE IRREGULAR CONNECTIVE TISSUE

102
Q

consists of freely branching elastic fibers, fibroblasts present between fibers

A

ELASTIC CONNECTIVE TISSUE

103
Q

Location : lung tissue, walls of elastic arteries, trachea, bronchial tubes, vocal cords, suspensory ligament of penis

A

ELASTIC CONNECTIVE TISSUE

104
Q

Function : allow stretching of various organs

A

ELASTIC CONNECTIVE TISSUE

105
Q

consists of adipocytes (cells that store triglycerides) in large central area in the cytoplasm, nuclei are peripherally located

A

ADIPOSE CONNECTIVE TISSUE

106
Q

Location : subcutaneous layer of skin, around heart and kidneys, yellow bone marrow, around joints and behind eyeball

A

ADIPOSE CONNECTIVE TISSUE

107
Q

Function : reduces heat loss through skin, serves as an energy reserve, supports and protects

A

ADIPOSE CONNECTIVE TISSUE

108
Q

network of interlacing reticular fibers

A

RETICULAR CONNECTIVE TISSUE

109
Q

Location : framework of liver, spleen and lymph nodes; red bone marrow

A

RETICULAR CONNECTIVE TISSUE

110
Q

Function : forms stroma of organs, binds together smooth muscle tissue

A

RETICULAR CONNECTIVE TISSUE

111
Q

Capable of enduring more stress to its collagen fibers

A

CARTILAGE CONNECTIVE TISSUE

112
Q

cells of mature cartilage, occur in singly or in groups among spaces called lacunae

A

CHONDROCYTES

113
Q

consists of bluish white and shiny ground substances with fine collagen fibers, numerous chondrocytes

A

HYALINE CARTILAGE

114
Q

Location : ends of long bones, anterior ends of ribs, nose, parts of larynx, trachea, bronchi, bronchial tubes, embryonic skeleton

A

HYALINE CARTILAGE

115
Q

consists of chondrocytes scattered among bundles of collagen fibers

A

FIBROCARTILAGE

116
Q

Function : provides smooth surfaces for movement at joints flexibility and support

A

HYALINE CARTILAGE

117
Q

Location : pubic symphysis, intervertebral discs, cartilage pads ok knees

Function : support and fusion

A

FIBROCARTILAGE

118
Q

consists of chondrocytes located in a threadlike network of elastic fibers

A

ELASTIC CARTILAGE

119
Q

Location : epiglottis, external ear, Eustachian tube

Function : gives support and maintains shape

A

ELASTIC CARTILAGE

120
Q

Comprise the skeletal system

A

Cartilage, joints and bone tissue

121
Q

Types of Bone Tissue

A

Compact Bones
Spongy Bones

122
Q

consists of osteons (haversian system) that contain lamellae, lacunae, osteocytes, canaliculi, and central canal

A

Compact Bone

123
Q

consists of thin plates called trabecullae, spaces between trabeculae are filled with red bone marrow

A

Spongy Bones

124
Q

Location : various bones of the body

A

BONE (OSSEOUS) TISSUE

125
Q

Function : support, protection, storage, house blood-forming tissues, act with muscle tissue to facilitate movement

A

BONE (OSSEOUS) TISSUE

126
Q

Connective tissue with fluid matrix called plasma which contains suspended materials known as blood cells

A

VASCULAR TISSUE (BLOOD)

127
Q

consists of plasma and formed elements (blood cells)

A

VASCULAR TISSUE (BLOOD)

128
Q

Location : within blood vessels

A

VASCULAR TISSUE (BLOOD)

129
Q

Function : RBC transport respiratory gases ; WBC involved in phagocytosis, allergic reaction and immunity; platelets are essential for blood clotting

A

VASCULAR TISSUE (BLOOD)