Module 4 Chapter 32 SUD part 1 basic considerations Flashcards
using a drug in a fashion inconsistent with medical or social norms
Drug abuse
defined as a cluster of cognitive, behavioral and physiological symptoms indicating that the individualized continues using the substance despite significant substance related problems
Substance Use diorder
results from regular drug use and can be defined as a state in which a particular dose elicits a smaller response than it did with initial use
Tolerance
a state in which tolerance to one drug confers tolerance to another within a particular class and not between drugs in different classes.
example
Cross tolerance
addicted to heroin, tolerant to morphine even if you have never had it
defined as an intense subjective need for a particular psychoactive drug
Psychological dependence
can be defined as a state in which an abstinence syndrome will occur if drug use is discontinued.
physical dependence
refers to the ability of one drug to support physical dependence on another drug.
explain
cross-dependence
alcohol and benzodiazepine
drug A will prevent withdrawal in drug B
a constellation of signs and symptoms that occurs in physically dependent individuals when they d/c drug use.
withdrawal syndrome
Being physically dependent on a drug is
the same/not the same as having a substance use disorder
not the same
what is the major neurotransmitter involved in the reward circuit for reinforcing behaviors
dopamine
phenomenon serves to reduce the response to drugs.
downregulation
does neural remodeling persist after drug use is stopped
the absence of pleasurable feelings from natural stimuli, the abuser is left feeling flat, lifeless and depressed. When the drug use stopped, neural remodeling tends to gradually reverse
what is the principal federal legislation addressing drug abuse
Controlled substance Act
enforcement of the CSA is the responsibility of the
Drug Enforcement Agency (DEA)
what approved uses for Schedule I drugs
no approved uses